Suzuki M - Search Results

1

Orexin 2 receptor-selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients.

Evans R, Kimura H, Alexander R, Davies CH, Faessel H, Hartman DS, Ishikawa T, Ratti E, Shimizu K, Suzuki M, Tanaka S, Yukitake H, Dauvilliers Y, Mignot E. Evans R, et al. Among authors: suzuki m. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2207531119. doi: 10.1073/pnas.2207531119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994639 Free PMC article.

2

A novel Na(+) -Independent alanine-serine-cysteine transporter 1 inhibitor inhibits both influx and efflux of D-Serine.

Sakimura K, Nakao K, Yoshikawa M, Suzuki M, Kimura H. Sakimura K, et al. Among authors: suzuki m. J Neurosci Res. 2016 Oct;94(10):888-95. doi: 10.1002/jnr.23772. Epub 2016 Jun 14. J Neurosci Res. 2016. PMID: 27302861

3

TAK-063, a phosphodiesterase 10A inhibitor, modulates neuronal activity in various brain regions in phMRI and EEG studies with and without ketamine challenge.

Tomimatsu Y, Cash D, Suzuki M, Suzuki K, Bernanos M, Simmons C, Williams SC, Kimura H. Tomimatsu Y, et al. Among authors: suzuki k, suzuki m. Neuroscience. 2016 Dec 17;339:180-190. doi: 10.1016/j.neuroscience.2016.10.006. Epub 2016 Oct 8. Neuroscience. 2016. PMID: 27725212

4

TAK-071, a novel M₁ positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects.

Sako Y, Kurimoto E, Mandai T, Suzuki A, Tanaka M, Suzuki M, Shimizu Y, Yamada M, Kimura H. Sako Y, et al. Among authors: suzuki m, suzuki a. Neuropsychopharmacology. 2019 Apr;44(5):950-960. doi: 10.1038/s41386-018-0168-8. Epub 2018 Aug 1. Neuropsychopharmacology. 2019. PMID: 30089885 Free PMC article.

5

TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window.

Kunugi A, Tanaka M, Suzuki A, Tajima Y, Suzuki N, Suzuki M, Nakamura S, Kuno H, Yokota A, Sogabe S, Kosugi Y, Awasaki Y, Kaku T, Kimura H. Kunugi A, et al. Among authors: suzuki m, suzuki n, suzuki a. Neuropsychopharmacology. 2019 Apr;44(5):961-970. doi: 10.1038/s41386-018-0213-7. Epub 2018 Sep 12. Neuropsychopharmacology. 2019. PMID: 30209408 Free PMC article.

6

TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys.

Kurimoto E, Nakashima M, Kimura H, Suzuki M. Kurimoto E, et al. Among authors: suzuki m. PLoS One. 2019 Mar 11;14(3):e0207969. doi: 10.1371/journal.pone.0207969. eCollection 2019. PLoS One. 2019. PMID: 30856192 Free PMC article.

7

Preclinical characterization of AMPA receptor potentiator TAK-137 as a therapeutic drug for schizophrenia.

Tanaka M, Kunugi A, Suzuki A, Suzuki N, Suzuki M, Kimura H. Tanaka M, et al. Among authors: suzuki m, suzuki n, suzuki a. Pharmacol Res Perspect. 2019 May 9;7(3):e00479. doi: 10.1002/prp2.479. eCollection 2019 Jun. Pharmacol Res Perspect. 2019. PMID: 31086673 Free PMC article.

8

In Vivo Pharmacological Comparison of TAK-071, a Positive Allosteric Modulator of Muscarinic M₁ Receptor, and Xanomeline, an Agonist of Muscarinic M₁/M₄ Receptor, in Rodents.

Mandai T, Kasahara M, Kurimoto E, Tanaka M, Suzuki M, Nakatani A, Kimura H. Mandai T, et al. Among authors: suzuki m. Neuroscience. 2019 Aug 21;414:60-76. doi: 10.1016/j.neuroscience.2019.07.003. Epub 2019 Jul 9. Neuroscience. 2019. PMID: 31299348

9

TAK-925, an orexin 2 receptor-selective agonist, shows robust wake-promoting effects in mice.

Yukitake H, Fujimoto T, Ishikawa T, Suzuki A, Shimizu Y, Rikimaru K, Ito M, Suzuki M, Kimura H. Yukitake H, et al. Among authors: suzuki m, suzuki a. Pharmacol Biochem Behav. 2019 Dec;187:172794. doi: 10.1016/j.pbb.2019.172794. Epub 2019 Oct 22. Pharmacol Biochem Behav. 2019. PMID: 31654653

10

Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement.

Suzuki A, Kunugi A, Tajima Y, Suzuki N, Suzuki M, Toyofuku M, Kuno H, Sogabe S, Kosugi Y, Awasaki Y, Kaku T, Kimura H. Suzuki A, et al. Among authors: suzuki m, suzuki n. Sci Rep. 2021 Jul 15;11(1):14532. doi: 10.1038/s41598-021-93888-0. Sci Rep. 2021. PMID: 34267258 Free PMC article.

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