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Page 1
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.
Folkersen L, Gustafsson S, Wang Q, Hansen DH, Hedman ÅK, Schork A, Page K, Zhernakova DV, Wu Y, Peters J, Eriksson N, Bergen SE, Boutin TS, Bretherick AD, Enroth S, Kalnapenkis A, Gådin JR, Suur BE, Chen Y, Matic L, Gale JD, Lee J, Zhang W, Quazi A, Ala-Korpela M, Choi SH, Claringbould A, Danesh J, Davey Smith G, de Masi F, Elmståhl S, Engström G, Fauman E, Fernandez C, Franke L, Franks PW, Giedraitis V, Haley C, Hamsten A, Ingason A, Johansson Å, Joshi PK, Lind L, Lindgren CM, Lubitz S, Palmer T, Macdonald-Dunlop E, Magnusson M, Melander O, Michaelsson K, Morris AP, Mägi R, Nagle MW, Nilsson PM, Nilsson J, Orho-Melander M, Polasek O, Prins B, Pålsson E, Qi T, Sjögren M, Sundström J, Surendran P, Võsa U, Werge T, Wernersson R, Westra HJ, Yang J, Zhernakova A, Ärnlöv J, Fu J, Smith JG, Esko T, Hayward C, Gyllensten U, Landen M, Siegbahn A, Wilson JF, Wallentin L, Butterworth AS, Holmes MV, Ingelsson E, Mälarstig A. Folkersen L, et al. Among authors: suur be. Nat Metab. 2020 Oct;2(10):1135-1148. doi: 10.1038/s42255-020-00287-2. Epub 2020 Oct 16. Nat Metab. 2020. PMID: 33067605 Free PMC article.
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.
Röhl S, Rykaczewska U, Seime T, Suur BE, Diez MG, Gådin JR, Gainullina A, Sergushichev AA, Wirka R, Lengquist M, Kronqvist M, Bergman O, Odeberg J, Lindeman JHN, Quertermous T, Hamsten A, Eriksson P, Hedin U, Razuvaev A, Matic LP. Röhl S, et al. Among authors: suur be. JVS Vasc Sci. 2020 Feb 7;1:13-27. doi: 10.1016/j.jvssci.2020.01.001. eCollection 2020. JVS Vasc Sci. 2020. PMID: 34617037 Free PMC article.
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.
Rykaczewska U, Suur BE, Röhl S, Razuvaev A, Lengquist M, Sabater-Lleal M, van der Laan SW, Miller CL, Wirka RC, Kronqvist M, Gonzalez Diez M, Vesterlund M, Gillgren P, Odeberg J, Lindeman JH, Veglia F, Humphries SE, de Faire U, Baldassarre D, Tremoli E; IMPROVE study group; Lehtiö J, Hansson GK, Paulsson-Berne G, Pasterkamp G, Quertermous T, Hamsten A, Eriksson P, Hedin U, Matic L. Rykaczewska U, et al. Among authors: suur be. Circ Res. 2020 Feb 28;126(5):571-585. doi: 10.1161/CIRCRESAHA.119.316063. Epub 2020 Jan 2. Circ Res. 2020. PMID: 31893970 Free article.
Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease.
Suur BE, Chemaly M, Lindquist Liljeqvist M, Djordjevic D, Stenemo M, Bergman O, Karlöf E, Lengquist M, Odeberg J, Hurt-Camejo E, Eriksson P, Ketelhuth DFJ, Roy J, Hedin U, Nyberg M, Matic L. Suur BE, et al. Front Pharmacol. 2022 Sep 15;13:988561. doi: 10.3389/fphar.2022.988561. eCollection 2022. Front Pharmacol. 2022. PMID: 36188622 Free PMC article.
Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis.
Mussbacher M, Salzmann M, Haigl B, Basílio J, Hochreiter B, Gleitsmann V, Moser B, Hoesel B, Suur BE, Puhm F, Ungerböck C, Kuttke M, Forteza MJ, Binder CJ, Ketelhuth DFJ, Assinger A, Schmid JA. Mussbacher M, et al. Among authors: suur be. Atherosclerosis. 2020 Aug;307:21-31. doi: 10.1016/j.atherosclerosis.2020.06.005. Epub 2020 Jul 6. Atherosclerosis. 2020. PMID: 32711212