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Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis.
Kugler M, Dellinger M, Kartnig F, Müller L, Preglej T, Heinz LX, Simader E, Göschl L, Puchner SE, Weiss S, Shaw LE, Farlik M, Weninger W, Superti-Furga G, Smolen JS, Steiner G, Aletaha D, Kiener HP, Lewis MJ, Pitzalis C, Tosevska A, Karonitsch T, Bonelli M. Kugler M, et al. Ann Rheum Dis. 2023 Sep;82(9):1142-1152. doi: 10.1136/ard-2022-223396. Epub 2023 Jun 21. Ann Rheum Dis. 2023. PMID: 37344156
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors.
Dvorak V, Casiraghi A, Colas C, Koren A, Tomek T, Offensperger F, Rukavina A, Tin G, Hahn E, Dobner S, Frommelt F, Boeszoermenyi A, Bernada V, Hannich JT, Ecker GF, Winter GE, Kubicek S, Superti-Furga G. Dvorak V, et al. Cell Chem Biol. 2023 Aug 17;30(8):953-964.e9. doi: 10.1016/j.chembiol.2023.06.029. Epub 2023 Jul 28. Cell Chem Biol. 2023. PMID: 37516113 Free PMC article.
Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8.
Ferrada E, Wiedmer T, Wang WA, Frommelt F, Steurer B, Klimek C, Lindinger S, Osthushenrich T, Garofoli A, Brocchetti S, Bradberry S, Huang J, MacNamara A, Scarabottolo L, Ecker GF, Malarstig A, Superti-Furga G. Ferrada E, et al. Among authors: superti furga g. J Mol Biol. 2024 Jan 15;436(2):168383. doi: 10.1016/j.jmb.2023.168383. Epub 2023 Dec 7. J Mol Biol. 2024. PMID: 38070861 Free article.
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2.
Polesel M, Wildschut MHE, Doucerain C, Kuhn M, Flace A, Steck AL, Wilhelm M, Ingles-Prieto A, Wiedmer T, Superti-Furga G, Manolova V, Dürrenberger F. Polesel M, et al. Among authors: superti furga g. Mitochondrion. 2024 Apr 29:101889. doi: 10.1016/j.mito.2024.101889. Online ahead of print. Mitochondrion. 2024. PMID: 38692382 Free article.
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Offensperger F, Tin G, Duran-Frigola M, Hahn E, Dobner S, Ende CWA, Strohbach JW, Rukavina A, Brennsteiner V, Ogilvie K, Marella N, Kladnik K, Ciuffa R, Majmudar JD, Field SD, Bensimon A, Ferrari L, Ferrada E, Ng A, Zhang Z, Degliesposti G, Boeszoermenyi A, Martens S, Stanton R, Müller AC, Hannich JT, Hepworth D, Superti-Furga G, Kubicek S, Schenone M, Winter GE. Offensperger F, et al. Among authors: superti furga g. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Science. 2024. PMID: 38662832
EU-LIFE charter of independent life science research institutes.
Superti-Furga G, Agostinho M, Bury J, Cook S, Durinx C, Ender A, van Luenen H, Lund AH, Medema RH, Miączyńska M, Nickel D, Pelicci PG, Puisieux A, Ripatti S, Sander M, Schubeler D, Serrano L, Sommer T, Sonne-Hansen K, Tomančák P, Vives J, Vontas J, Bettencourt-Dias M. Superti-Furga G, et al. FEBS Lett. 2024 Apr;598(7):719-724. doi: 10.1002/1873-3468.14855. Epub 2024 Mar 21. FEBS Lett. 2024. PMID: 38514456
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling.
Ng A, Offensperger F, Cisneros JA, Scholes NS, Malik M, Villanti L, Rukavina A, Ferrada E, Hannich JT, Koren A, Kubicek S, Superti-Furga G, Winter GE. Ng A, et al. Among authors: superti furga g. ACS Chem Biol. 2023 Dec 15;18(12):2464-2473. doi: 10.1021/acschembio.3c00598. Epub 2023 Nov 21. ACS Chem Biol. 2023. PMID: 38098458 Free PMC article.
Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Chen X, Xie M, Zhang S, Monguió-Tortajada M, Yin J, Liu C, Zhang Y, Delacrétaz M, Song M, Wang Y, Dong L, Ding Q, Zhou B, Tian X, Deng H, Xu L, Liu X, Yang Z, Chang Q, Na J, Zeng W, Superti-Furga G, Rebsamen M, Yang M. Chen X, et al. Among authors: superti furga g. Nat Commun. 2023 Oct 20;14(1):6627. doi: 10.1038/s41467-023-42210-9. Nat Commun. 2023. PMID: 37863913 Free PMC article.
279 results