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Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates.
Du Y, Liang Z, Wang S, Sun D, Wang X, Liew SY, Lu S, Wu S, Jiang Y, Wang Y, Zhang B, Yu W, Lu Z, Pu Y, Zhang Y, Long H, Xiao S, Liang R, Zhang Z, Guan J, Wang J, Ren H, Wei Y, Zhao J, Sun S, Liu T, Meng G, Wang L, Gu J, Wang T, Liu Y, Li C, Tang C, Shen Z, Peng X, Deng H. Du Y, et al. Among authors: sun s, sun d. Nat Med. 2022 Feb;28(2):272-282. doi: 10.1038/s41591-021-01645-7. Epub 2022 Feb 3. Nat Med. 2022. PMID: 35115708
Long-term functional maintenance of primary human hepatocytes in vitro.
Xiang C, Du Y, Meng G, Soon Yi L, Sun S, Song N, Zhang X, Xiao Y, Wang J, Yi Z, Liu Y, Xie B, Wu M, Shu J, Sun D, Jia J, Liang Z, Sun D, Huang Y, Shi Y, Xu J, Lu F, Li C, Xiang K, Yuan Z, Lu S, Deng H. Xiang C, et al. Among authors: sun s, sun d. Science. 2019 Apr 26;364(6438):399-402. doi: 10.1126/science.aau7307. Science. 2019. PMID: 31023926
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts.
Xie B, Sun D, Du Y, Jia J, Sun S, Xu J, Liu Y, Xiang C, Chen S, Xie H, Wang Q, Li G, Lyu X, Shen H, Li S, Wu M, Zhang X, Pu Y, Xiang K, Lai W, Du P, Yuan Z, Li C, Shi Y, Lu S, Deng H. Xie B, et al. Among authors: sun s, sun d. Cell Res. 2019 Sep;29(9):696-710. doi: 10.1038/s41422-019-0196-x. Epub 2019 Jul 3. Cell Res. 2019. PMID: 31270412 Free PMC article.
In vivo chemical reprogramming of astrocytes into neurons.
Ma Y, Xie H, Du X, Wang L, Jin X, Zhang Q, Han Y, Sun S, Wang L, Li X, Zhang C, Wang M, Li C, Xu J, Huang Z, Wang X, Chai Z, Deng H. Ma Y, et al. Among authors: sun s. Cell Discov. 2021 Mar 2;7(1):12. doi: 10.1038/s41421-021-00243-8. Cell Discov. 2021. PMID: 33649311 Free PMC article.
Chemical reprogramming of human somatic cells to pluripotent stem cells.
Guan J, Wang G, Wang J, Zhang Z, Fu Y, Cheng L, Meng G, Lyu Y, Zhu J, Li Y, Wang Y, Liuyang S, Liu B, Yang Z, He H, Zhong X, Chen Q, Zhang X, Sun S, Lai W, Shi Y, Liu L, Wang L, Li C, Lu S, Deng H. Guan J, et al. Among authors: sun s. Nature. 2022 May;605(7909):325-331. doi: 10.1038/s41586-022-04593-5. Epub 2022 Apr 13. Nature. 2022. PMID: 35418683
Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets.
Liang Z, Sun D, Lu S, Lei Z, Wang S, Luo Z, Zhan J, Wu S, Jiang Y, Lu Z, Sun S, Shi Y, Long H, Wei Y, Yu W, Wang Z, Yi LS, Zhang Y, Sun W, Fang X, Li Y, Lu S, Lv J, Sui W, Shen Z, Peng X, Du Y, Deng H. Liang Z, et al. Among authors: sun s, sun w, sun d. Nat Metab. 2023 Jan;5(1):29-40. doi: 10.1038/s42255-022-00713-7. Epub 2023 Jan 9. Nat Metab. 2023. PMID: 36624157
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