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An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z, Wang K, Lu L, Sun L, Wang Q. Liu Z, et al. Among authors: sun l. Protein Cell. 2022 Sep;13(9):655-675. doi: 10.1007/s13238-021-00871-6. Epub 2021 Sep 23. Protein Cell. 2022. PMID: 34554412 Free PMC article.
Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Liu Q, Zhang X, Huang H, Chen Y, Wang F, Hao A, Zhan W, Mao Q, Hu Y, Han L, Sun Y, Zhang M, Liu Z, Li GL, Zhang W, Shu Y, Sun L, Chen Z. Liu Q, et al. Among authors: sun l, sun y. Nat Commun. 2023 May 25;14(1):3012. doi: 10.1038/s41467-023-38303-0. Nat Commun. 2023. PMID: 37230976 Free PMC article.
Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Wang H, Yang Q, Liu X, Xu Z, Shao M, Li D, Duan Y, Tang J, Yu X, Zhang Y, Hao A, Wang Y, Chen J, Zhu C, Guddat L, Chen H, Zhang L, Chen X, Jiang B, Sun L, Rao Z, Yang H. Wang H, et al. Among authors: sun l. Nat Commun. 2023 Nov 21;14(1):7574. doi: 10.1038/s41467-023-42527-5. Nat Commun. 2023. PMID: 37990007 Free PMC article.
Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination.
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P. Zhao X, et al. Among authors: sun l. Cell Discov. 2024 Feb 6;10(1):14. doi: 10.1038/s41421-024-00648-1. Cell Discov. 2024. PMID: 38320990 Free PMC article.
Evolution of a chordate-specific mechanism for myoblast fusion.
Zhang H, Shang R, Kim K, Zheng W, Johnson CJ, Sun L, Niu X, Liu L, Zhou J, Liu L, Zhang Z, Uyeno TA, Pei J, Fissette SD, Green SA, Samudra SP, Wen J, Zhang J, Eggenschwiler JT, Menke DB, Bronner ME, Grishin NV, Li W, Ye K, Zhang Y, Stolfi A, Bi P. Zhang H, et al. Among authors: sun l. Sci Adv. 2022 Sep 2;8(35):eadd2696. doi: 10.1126/sciadv.add2696. Epub 2022 Sep 2. Sci Adv. 2022. PMID: 36054355 Free PMC article.
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