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Page 1
Human metabolic individuality in biomedical and pharmaceutical research.
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E; CARDIoGRAM; Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C. Suhre K, et al. Nature. 2011 Aug 31;477(7362):54-60. doi: 10.1038/nature10354. Nature. 2011. PMID: 21886157 Free PMC article.
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.
Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U; MolPAGE Consortium; Donnelly P, Illig T, Adamski J, Suhre K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D, Holmes E, McCarthy MI, Holmes CC. Nicholson G, et al. Among authors: suhre k. PLoS Genet. 2011 Sep;7(9):e1002270. doi: 10.1371/journal.pgen.1002270. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931564 Free PMC article.
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium; Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Claussnitzer M, et al. Among authors: suhre k. Cell. 2014 Jan 16;156(1-2):343-58. doi: 10.1016/j.cell.2013.10.058. Cell. 2014. PMID: 24439387 Free PMC article.
An atlas of genetic influences on human blood metabolites.
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E; Multiple Tissue Human Expression Resource (MuTHER) Consortium; Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenmüller G, Spector TD, Soranzo N. Shin SY, et al. Among authors: suhre k. Nat Genet. 2014 Jun;46(6):543-550. doi: 10.1038/ng.2982. Epub 2014 May 11. Nat Genet. 2014. PMID: 24816252 Free PMC article.
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.
Draisma HHM, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AAM, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Böhringer S, Beekman M, van Klinken JB, Römisch-Margl W, Prehn C, Adamski J, de Craen AJM, van Leeuwen EM, Amin N, Dharuri H, Westra HJ, Franke L, de Geus EJC, Hottenga JJ, Willemsen G, Henders AK, Montgomery GW, Nyholt DR, Whitfield JB, Penninx BW, Spector TD, Metspalu A, Slagboom PE, van Dijk KW, 't Hoen PAC, Strauch K, Martin NG, van Ommen GB, Illig T, Bell JT, Mangino M, Suhre K, McCarthy MI, Gieger C, Isaacs A, van Duijn CM, Boomsma DI. Draisma HHM, et al. Among authors: suhre k. Nat Commun. 2015 Jun 12;6:7208. doi: 10.1038/ncomms8208. Nat Commun. 2015. PMID: 26068415 Free PMC article.
Genetics of human metabolism: an update.
Kastenmüller G, Raffler J, Gieger C, Suhre K. Kastenmüller G, et al. Among authors: suhre k. Hum Mol Genet. 2015 Oct 15;24(R1):R93-R101. doi: 10.1093/hmg/ddv263. Epub 2015 Jul 9. Hum Mol Genet. 2015. PMID: 26160913 Free PMC article. Review.
Connecting genetic risk to disease end points through the human blood plasma proteome.
Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J. Suhre K, et al. Nat Commun. 2017 Feb 27;8:14357. doi: 10.1038/ncomms14357. Nat Commun. 2017. PMID: 28240269 Free PMC article.
297 results