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Membrane transporters in drug development.
International Transporter Consortium; Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. International Transporter Consortium, et al. Among authors: sugiyama y. Nat Rev Drug Discov. 2010 Mar;9(3):215-36. doi: 10.1038/nrd3028. Nat Rev Drug Discov. 2010. PMID: 20190787 Free PMC article. Review.
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium.
Chu X, Liao M, Shen H, Yoshida K, Zur AA, Arya V, Galetin A, Giacomini KM, Hanna I, Kusuhara H, Lai Y, Rodrigues D, Sugiyama Y, Zamek-Gliszczynski MJ, Zhang L; International Transporter Consortium. Chu X, et al. Among authors: sugiyama y. Clin Pharmacol Ther. 2018 Nov;104(5):836-864. doi: 10.1002/cpt.1216. Clin Pharmacol Ther. 2018. PMID: 30347454 Review.
Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance.
Zamek-Gliszczynski MJ, Sangha V, Shen H, Feng B, Wittwer MB, Varma MVS, Liang X, Sugiyama Y, Zhang L, Bendayan R; International Transporter Consortium. Zamek-Gliszczynski MJ, et al. Among authors: sugiyama y. Clin Pharmacol Ther. 2022 Sep;112(3):485-500. doi: 10.1002/cpt.2644. Epub 2022 Jun 29. Clin Pharmacol Ther. 2022. PMID: 35561119 Review.
Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.
Zamek-Gliszczynski MJ, Patel M, Yang X, Lutz JD, Chu X, Brouwer KLR, Lai Y, Lee CA, Neuhoff S, Paine MF, Sugiyama Y, Taskar KS, Galetin A. Zamek-Gliszczynski MJ, et al. Among authors: sugiyama y. Clin Pharmacol Ther. 2021 Jan;109(1):55-64. doi: 10.1002/cpt.1916. Epub 2020 Jul 9. Clin Pharmacol Ther. 2021. PMID: 32460379 Free PMC article. Review.
Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches.
Guo Y, Chu X, Parrott NJ, Brouwer KLR, Hsu V, Nagar S, Matsson P, Sharma P, Snoeys J, Sugiyama Y, Tatosian D, Unadkat JD, Huang SM, Galetin A; International Transporter Consortium. Guo Y, et al. Among authors: sugiyama y. Clin Pharmacol Ther. 2018 Nov;104(5):865-889. doi: 10.1002/cpt.1183. Epub 2018 Sep 12. Clin Pharmacol Ther. 2018. PMID: 30059145 Free PMC article.
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.
Taskar KS, Yang X, Neuhoff S, Patel M, Yoshida K, Paine MF, Brouwer KLR, Chu X, Sugiyama Y, Cook J, Polli JW, Hanna I, Lai Y, Zamek-Gliszczynski M; ITC. Taskar KS, et al. Among authors: sugiyama y. Clin Pharmacol Ther. 2022 Sep;112(3):573-592. doi: 10.1002/cpt.2670. Epub 2022 Jun 22. Clin Pharmacol Ther. 2022. PMID: 35612761 Free PMC article. Review.
2,656 results