Subelzu N - Search Results

1

Probing Protein Conformation Destabilization in Sterile Liquid Formulations through the Formation of 3,4-Dihydroxyphenylalanine.

Mozziconacci O, Subelzu N, Schöneich C, Liu Y, Abend A, Wuelfing WP. Mozziconacci O, et al. Among authors: subelzu n. Mol Pharm. 2020 Oct 5;17(10):3783-3793. doi: 10.1021/acs.molpharmaceut.0c00554. Epub 2020 Sep 24. Mol Pharm. 2020. PMID: 32910663

2

Near UV and Visible Light Induce Iron-Dependent Photodegradation Reactions in Pharmaceutical Buffers: Mechanistic and Product Studies.

Subelzu N, Schöneich C. Subelzu N, et al. Mol Pharm. 2020 Nov 2;17(11):4163-4179. doi: 10.1021/acs.molpharmaceut.0c00639. Epub 2020 Oct 8. Mol Pharm. 2020. PMID: 32986444

3

Identification of D-Amino Acids in Light Exposed mAb Formulations.

Bommana R, Subelzu N, Mozziconacci O, Sreedhara A, Schöneich C. Bommana R, et al. Among authors: subelzu n. Pharm Res. 2018 Oct 17;35(11):238. doi: 10.1007/s11095-018-2520-4. Pharm Res. 2018. PMID: 30334107

4

Pharmaceutical Excipients Enhance Iron-Dependent Photo-Degradation in Pharmaceutical Buffers by near UV and Visible Light: Tyrosine Modification by Reactions of the Antioxidant Methionine in Citrate Buffer.

Subelzu N, Schöneich C. Subelzu N, et al. Pharm Res. 2021 May;38(5):915-930. doi: 10.1007/s11095-021-03042-8. Epub 2021 Apr 21. Pharm Res. 2021. PMID: 33881737

5

Near UV and Visible Light Photo-Degradation Mechanisms in Citrate Buffer: One-Electron Reduction of Peptide and Protein Disulfides promotes Oxidation and Cis/Trans Isomerization of Unsaturated Fatty Acids of Polysorbate 80.

Prajapati I, Subelzu N, Zhang Y, Wu Y, Schöneich C. Prajapati I, et al. Among authors: subelzu n. J Pharm Sci. 2022 Apr;111(4):991-1003. doi: 10.1016/j.xphs.2022.01.026. Epub 2022 Jan 31. J Pharm Sci. 2022. PMID: 35108563

6

Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation.

Song JY, Larson NR, Thati S, Torres-Vazquez I, Martinez-Rivera N, Subelzu NJ, Leon MA, Rosa-Molinar E, Schöneich C, Forrest ML, Middaugh CR, Berkland CJ. Song JY, et al. Among authors: subelzu nj. J Control Release. 2019 Jan 10;293:36-47. doi: 10.1016/j.jconrel.2018.11.007. Epub 2018 Nov 7. J Control Release. 2019. PMID: 30414463 Free PMC article.

7

Validation of a Caco-2 microfluidic Chip model for predicting intestinal absorption of BCS Class I-IV drugs.

Zhang SY, Ong WSY, Subelzu N, Gleeson JP. Zhang SY, et al. Among authors: subelzu n. Int J Pharm. 2024 May 10;656:124089. doi: 10.1016/j.ijpharm.2024.124089. Epub 2024 Apr 8. Int J Pharm. 2024. PMID: 38599444

8

Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of peroxiredoxins.

Fiuza B, Subelzú N, Calcerrada P, Straliotto MR, Piacenza L, Cassina A, Rocha JB, Radi R, de Bem AF, Peluffo G. Fiuza B, et al. Among authors: subelzu n. Free Radic Res. 2015 Feb;49(2):122-32. doi: 10.3109/10715762.2014.983096. Epub 2014 Nov 28. Free Radic Res. 2015. PMID: 25373783

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