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Page 1
HMGB1 as a therapeutic target in disease.
Xue J, Suarez JS, Minaai M, Li S, Gaudino G, Pass HI, Carbone M, Yang H. Xue J, et al. Among authors: suarez js. J Cell Physiol. 2021 May;236(5):3406-3419. doi: 10.1002/jcp.30125. Epub 2020 Oct 26. J Cell Physiol. 2021. PMID: 33107103 Free PMC article. Review.
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy.
Xue J, Patergnani S, Giorgi C, Suarez J, Goto K, Bononi A, Tanji M, Novelli F, Pastorino S, Xu R, Caroccia N, Dogan AU, Pass HI, Tognon M, Pinton P, Gaudino G, Mak TW, Carbone M, Yang H. Xue J, et al. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25543-25552. doi: 10.1073/pnas.2007622117. Epub 2020 Sep 30. Proc Natl Acad Sci U S A. 2020. PMID: 32999071 Free PMC article.
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.
Bononi A, Goto K, Ak G, Yoshikawa Y, Emi M, Pastorino S, Carparelli L, Ferro A, Nasu M, Kim JH, Suarez JS, Xu R, Tanji M, Takinishi Y, Minaai M, Novelli F, Pagano I, Gaudino G, Pass HI, Groden J, Grzymski JJ, Metintas M, Akarsu M, Morrow B, Hassan R, Yang H, Carbone M. Bononi A, et al. Among authors: suarez js. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33466-33473. doi: 10.1073/pnas.2019652117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318203 Free PMC article.
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos.
Novelli F, Bononi A, Wang Q, Bai F, Patergnani S, Kricek F, Haglund E, Suarez JS, Tanji M, Xu R, Takanishi Y, Minaai M, Pastorino S, Morris P, Sakamoto G, Pass HI, Barbour H, Gaudino G, Giorgi C, Pinton P, Onuchic JN, Yang H, Carbone M. Novelli F, et al. Among authors: suarez js. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2111946118. doi: 10.1073/pnas.2111946118. Proc Natl Acad Sci U S A. 2021. PMID: 34815344 Free PMC article.
BAP1 is a novel regulator of HIF-1α.
Bononi A, Wang Q, Zolondick AA, Bai F, Steele-Tanji M, Suarez JS, Pastorino S, Sipes A, Signorato V, Ferro A, Novelli F, Kim JH, Minaai M, Takinishi Y, Pellegrini L, Napolitano A, Xu R, Farrar C, Goparaju C, Bassi C, Negrini M, Pagano I, Sakamoto G, Gaudino G, Pass HI, Onuchic JN, Yang H, Carbone M. Bononi A, et al. Among authors: suarez js. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217840120. doi: 10.1073/pnas.2217840120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656861 Free PMC article.
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma.
Suarez JS, Novelli F, Goto K, Ehara M, Steele M, Kim JH, Zolondick AA, Xue J, Xu R, Saito M, Pastorino S, Minaai M, Takanishi Y, Emi M, Pagano I, Wakeham A, Berger T, Pass HI, Gaudino G, Mak TW, Carbone M, Yang H. Suarez JS, et al. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2307999120. doi: 10.1073/pnas.2307999120. Epub 2023 Sep 20. Proc Natl Acad Sci U S A. 2023. PMID: 37729199 Free PMC article.
Neurolight: A Deep Learning Neural Interface for Cortical Visual Prostheses.
Lozano A, Suárez JS, Soto-Sánchez C, Garrigós J, Martínez-Alvarez JJ, Ferrández JM, Fernández E. Lozano A, et al. Among authors: suarez js. Int J Neural Syst. 2020 Sep;30(9):2050045. doi: 10.1142/S0129065720500458. Epub 2020 Jul 21. Int J Neural Syst. 2020. PMID: 32689842