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Endothelial PFKFB3 plays a critical role in angiogenesis.
Xu Y, An X, Guo X, Habtetsion TG, Wang Y, Xu X, Kandala S, Li Q, Li H, Zhang C, Caldwell RB, Fulton DJ, Su Y, Hoda MN, Zhou G, Wu C, Huo Y. Xu Y, et al. Among authors: su y. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1231-9. doi: 10.1161/ATVBAHA.113.303041. Epub 2014 Apr 3. Arterioscler Thromb Vasc Biol. 2014. PMID: 24700124 Free PMC article.
Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction.
Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R. Czikora I, et al. Among authors: su y. Front Immunol. 2017 Jul 21;8:842. doi: 10.3389/fimmu.2017.00842. eCollection 2017. Front Immunol. 2017. PMID: 28785264 Free PMC article.
Hsp70 Suppresses Mitochondrial Reactive Oxygen Species and Preserves Pulmonary Microvascular Barrier Integrity Following Exposure to Bacterial Toxins.
Li X, Yu Y, Gorshkov B, Haigh S, Bordan Z, Weintraub D, Rudic RD, Chakraborty T, Barman SA, Verin AD, Su Y, Lucas R, Stepp DW, Chen F, Fulton DJR. Li X, et al. Among authors: su y. Front Immunol. 2018 Jun 12;9:1309. doi: 10.3389/fimmu.2018.01309. eCollection 2018. Front Immunol. 2018. PMID: 29951058 Free PMC article.
PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
Cao Y, Zhang X, Wang L, Yang Q, Ma Q, Xu J, Wang J, Kovacs L, Ayon RJ, Liu Z, Zhang M, Zhou Y, Zeng X, Xu Y, Wang Y, Fulton DJ, Weintraub NL, Lucas R, Dong Z, Yuan JX, Sullivan JC, Meadows L, Barman SA, Wu C, Quan J, Hong M, Su Y, Huo Y. Cao Y, et al. Among authors: su y. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13394-13403. doi: 10.1073/pnas.1821401116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213542 Free PMC article.
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