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Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity".
Decara JM, Vázquez-Villa H, Brea J, Alonso M, Srivastava RK, Orio L, Alén F, Suárez J, Baixeras E, García-Cárceles J, Escobar-Peña A, Lutz B, Rodríguez R, Codesido E, Garcia-Ladona FJ, Bennett TA, Ballesteros JA, Cruces J, Loza MI, Benhamú B, Rodríguez de Fonseca F, López-Rodríguez ML. Decara JM, et al. Among authors: suarez j. J Med Chem. 2022 Apr 14;65(7):5449-5461. doi: 10.1021/acs.jmedchem.1c01842. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349261 Free PMC article.
Anti-obesity efficacy of LH-21, a cannabinoid CB(1) receptor antagonist with poor brain penetration, in diet-induced obese rats.
Alonso M, Serrano A, Vida M, Crespillo A, Hernandez-Folgado L, Jagerovic N, Goya P, Reyes-Cabello C, Perez-Valero V, Decara J, Macías-González M, Bermúdez-Silva FJ, Suárez J, Rodríguez de Fonseca F, Pavón FJ. Alonso M, et al. Among authors: suarez j. Br J Pharmacol. 2012 Apr;165(7):2274-91. doi: 10.1111/j.1476-5381.2011.01698.x. Br J Pharmacol. 2012. PMID: 21951309 Free PMC article.
Adiponectin promoter activator NP-1 reduces body weight and hepatic steatosis in high-fat diet-fed animals.
Serrano A, Pavón FJ, Suarez J, Rivera P, Vida M, Bermúdez-Silva FJ, Alonso M, Martínez A, López-Ogalla J, Alonso-Gascón M, Santamaría G, Romero-Cuevas M, Pérez-Valero V, Baixeras E, Rodríguez de Fonseca F. Serrano A, et al. Among authors: suarez j. Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E817-30. doi: 10.1152/ajpendo.00468.2011. Epub 2012 Jan 31. Am J Physiol Endocrinol Metab. 2012. PMID: 22297300 Free article.
Elaidyl-sulfamide, an oleoylethanolamide-modelled PPARα agonist, reduces body weight gain and plasma cholesterol in rats.
Decara JM, Romero-Cuevas M, Rivera P, Macias-González M, Vida M, Pavón FJ, Serrano A, Cano C, Fresno N, Pérez-Fernández R, Rodríguez de Fonseca F, Suárez J. Decara JM, et al. Among authors: suarez j. Dis Model Mech. 2012 Sep;5(5):660-70. doi: 10.1242/dmm.009233. Epub 2012 Jun 26. Dis Model Mech. 2012. PMID: 22736460 Free PMC article.
CB1 blockade potentiates down-regulation of lipogenic gene expression in perirenal adipose tissue in high carbohydrate diet-induced obesity.
Vida M, Rivera P, Gavito AL, Suárez J, Pavón FJ, Arrabal S, Romero-Cuevas M, Bautista D, Martínez A, de Fonseca FR, Serrano A, Baixeras E. Vida M, et al. Among authors: suarez j. PLoS One. 2014 Feb 25;9(2):e90016. doi: 10.1371/journal.pone.0090016. eCollection 2014. PLoS One. 2014. PMID: 24587189 Free PMC article.
Effects of acute versus repeated cocaine exposure on the expression of endocannabinoid signaling-related proteins in the mouse cerebellum.
Palomino A, Pavón FJ, Blanco-Calvo E, Serrano A, Arrabal S, Rivera P, Alén F, Vargas A, Bilbao A, Rubio L, Rodríguez de Fonseca F, Suárez J. Palomino A, et al. Among authors: suarez j. Front Integr Neurosci. 2014 Mar 5;8:22. doi: 10.3389/fnint.2014.00022. eCollection 2014. Front Integr Neurosci. 2014. PMID: 24634647 Free PMC article.
1,631 results