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Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Gomez K, Stratton HJ, Duran P, Loya S, Tang C, Calderon-Rivera A, François-Moutal L, Khanna M, Madura CL, Luo S, McKiver B, Choi E, Ran D, Boinon L, Perez-Miller S, Damaj MI, Moutal A, Khanna R. Gomez K, et al. Among authors: stratton hj. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2217800120. doi: 10.1073/pnas.2217800120. Epub 2023 Jul 27. Proc Natl Acad Sci U S A. 2023. PMID: 37498871 Free PMC article.
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+ Channels and Pain.
Gomez K, Tang C, Tan B, Perez-Miller S, Ran D, Loya S, Calderon-Rivera A, Stratton HJ, Duran P, Masterson KA, Gabrielsen AT, Alsbiei O, Dorame A, Serafini M, Moutal A, Wang J, Khanna R. Gomez K, et al. Among authors: stratton hj. ACS Chem Neurosci. 2022 Jul 6;13(13):2035-2047. doi: 10.1021/acschemneuro.2c00256. Epub 2022 Jun 7. ACS Chem Neurosci. 2022. PMID: 35671441
The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Duran P, Loya-López S, Ran D, Tang C, Calderon-Rivera A, Gomez K, Stratton HJ, Huang S, Xu YM, Wijeratne EMK, Perez-Miller S, Shan Z, Cai S, Gabrielsen AT, Dorame A, Masterson KA, Alsbiei O, Madura CL, Luo G, Moutal A, Streicher J, Zamponi GW, Gunatilaka AAL, Khanna R. Duran P, et al. Among authors: stratton hj. Br J Pharmacol. 2023 May;180(9):1267-1285. doi: 10.1111/bph.15974. Epub 2023 Jan 15. Br J Pharmacol. 2023. PMID: 36245395 Free article.
Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Calderon-Rivera A, Gomez K, Loya-López S, Wijeratne EMK, Stratton H, Tang C, Duran P, Masterson K, Alsbiei O, Gunatilaka AAL, Khanna R. Calderon-Rivera A, et al. Neurobiol Pain. 2023 Jan 14;13:100116. doi: 10.1016/j.ynpai.2023.100116. eCollection 2023 Jan-Jul. Neurobiol Pain. 2023. PMID: 36687466 Free PMC article.
Coordinating Synaptic Signaling with CRMP2.
Stratton H, Boinon L, Moutal A, Khanna R. Stratton H, et al. Int J Biochem Cell Biol. 2020 Jul;124:105759. doi: 10.1016/j.biocel.2020.105759. Epub 2020 May 8. Int J Biochem Cell Biol. 2020. PMID: 32437854 Review.
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