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2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.
Bolli MH, Abele S, Binkert C, Bravo R, Buchmann S, Bur D, Gatfield J, Hess P, Kohl C, Mangold C, Mathys B, Menyhart K, Müller C, Nayler O, Scherz M, Schmidt G, Sippel V, Steiner B, Strasser D, Treiber A, Weller T. Bolli MH, et al. J Med Chem. 2010 May 27;53(10):4198-211. doi: 10.1021/jm100181s. J Med Chem. 2010. PMID: 20446681
Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental Hypertension.
Trensz F, Bortolamiol C, Kramberg M, Wanner D, Hadana H, Rey M, Strasser DS, Delahaye S, Hess P, Vezzali E, Mentzel U, Ménard J, Clozel M, Iglarz M. Trensz F, et al. Among authors: strasser ds. J Pharmacol Exp Ther. 2019 Mar;368(3):462-473. doi: 10.1124/jpet.118.253864. Epub 2019 Jan 8. J Pharmacol Exp Ther. 2019. PMID: 30622171
Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus.
Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, Murphy MJ. Strasser DS, et al. RMD Open. 2020 Sep;6(2):e001261. doi: 10.1136/rmdopen-2020-001261. RMD Open. 2020. PMID: 32917831 Free PMC article.
CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis.
Pouzol L, Sassi A, Baumlin N, Tunis M, Strasser DS, Lehembre F, Martinic MM. Pouzol L, et al. Among authors: strasser ds. Front Pharmacol. 2021 Nov 5;12:748740. doi: 10.3389/fphar.2021.748740. eCollection 2021. Front Pharmacol. 2021. PMID: 34803691 Free PMC article.
Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes.
Christen U, Pouzol L, Tunis M, Sassi A, Tondello C, Bayer M, Hintermann E, Strasser DS, Schuldes S, Mentzel U, Martinic MM. Christen U, et al. Among authors: strasser ds. Clin Exp Immunol. 2023 Dec 12;214(2):131-143. doi: 10.1093/cei/uxad083. Clin Exp Immunol. 2023. PMID: 37458220 Free PMC article.
33 results