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Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model.
Zancanella V, Vallès A, Liefhebber JMP, Paerels L, Tornero CV, Wattimury H, van der Zon T, van Rooijen K, Golinska M, Grevelink T, Ehlert E, Pieterman EJ, Keijzer N, Princen HMG, Stokman G, Liu YP. Zancanella V, et al. Among authors: stokman g. Mol Ther Nucleic Acids. 2023 Apr 7;32:454-467. doi: 10.1016/j.omtn.2023.04.004. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37168797 Free PMC article.
Erratum: Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model.
Zancanella V, Vallès A, Liefhebber JMP, Paerels L, Tornero CV, Wattimury H, van der Zon T, van Rooijen K, Golinska M, Grevelink T, Ehlert E, Pieterman EJ, Keijzer N, Gerardus Princen HM, Stokman G, Liu YP. Zancanella V, et al. Among authors: stokman g. Mol Ther Nucleic Acids. 2024 Apr 18;35(2):102189. doi: 10.1016/j.omtn.2024.102189. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38681817 Free PMC article.
A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo.
Suchowerska AK, Stokman G, Palmer JT, Coghlan PA, Pieterman EJ, Keijzer N, Lambert G, Chemello K, Jaafar AK, Parmar J, Yan L, Tong Y, Mu L, Princen HMG, Bonnar J, Evison BJ. Suchowerska AK, et al. Among authors: stokman g. J Lipid Res. 2022 Nov;63(11):100293. doi: 10.1016/j.jlr.2022.100293. Epub 2022 Oct 6. J Lipid Res. 2022. PMID: 36209894 Free PMC article.
Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.
Stokman G, van den Hoek AM, Denker Thorbekk D, Pieterman EJ, Skovgård Veidal S, Basta B, Iruarrizaga-Lejarreta M, van der Hoorn JW, Verschuren L, Berbée JFP, Rensen PCN, Skjaeret T, Alonso C, Feigh M, Kastelein JJP, Friedman SL, Princen HMG, Fraser DA. Stokman G, et al. Liver Int. 2020 Nov;40(11):2860-2876. doi: 10.1111/liv.14643. Liver Int. 2020. PMID: 32841505 Free PMC article.
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.
Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC. Kors L, et al. Among authors: stokman g. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1883-1895. doi: 10.1016/j.bbadis.2018.03.003. Epub 2018 Mar 4. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29514047 Free article.
30 results