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Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.
Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Ordulu Z, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Mahamdeh MS, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Oliva E, Rueda BR, Soberman RJ, Bardeesy N, Liau BB, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L. Zhang J, et al. Among authors: stokes mp. Cell. 2023 May 25;186(11):2361-2379.e25. doi: 10.1016/j.cell.2023.04.026. Epub 2023 May 15. Cell. 2023. PMID: 37192619
Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells.
Amiri M, Kiniry SJ, Possemato AP, Mahmood N, Basiri T, Dufour CR, Tabatabaei N, Deng Q, Bellucci MA, Harwalkar K, Stokes MP, Giguère V, Kaufman RJ, Yamanaka Y, Baranov PV, Tahmasebi S, Sonenberg N. Amiri M, et al. Among authors: stokes mp. Cell Rep. 2024 Jan 23;43(1):113615. doi: 10.1016/j.celrep.2023.113615. Epub 2023 Dec 29. Cell Rep. 2024. PMID: 38159280 Free PMC article.
Cdk5 mediates rotational force-induced brain injury.
Umfress A, Chakraborti A, Priya Sudarsana Devi S, Adams R, Epstein D, Massicano A, Sorace A, Singh S, Iqbal Hossian M, Andrabi SA, Crossman DK, Kumar N, Shahid Mukhtar M, Luo H, Simpson C, Abell K, Stokes M, Wiederhold T, Rosen C, Lu H, Natarajan A, Bibb JA. Umfress A, et al. Sci Rep. 2023 Feb 28;13(1):3394. doi: 10.1038/s41598-023-29322-4. Sci Rep. 2023. PMID: 36854738 Free PMC article.
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.
Reichlmeir M, Canet-Pons J, Koepf G, Nurieva W, Duecker RP, Doering C, Abell K, Key J, Stokes MP, Zielen S, Schubert R, Ivics Z, Auburger G. Reichlmeir M, et al. Among authors: stokes mp. Cells. 2023 Oct 3;12(19):2399. doi: 10.3390/cells12192399. Cells. 2023. PMID: 37830614 Free PMC article.
Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway.
Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Sahin ZO, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Olivia E, Rueda B, Bardeesy N, Liau B, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L. Zhang J, et al. Among authors: stokes mp. bioRxiv [Preprint]. 2023 Mar 11:2023.03.11.532189. doi: 10.1101/2023.03.11.532189. bioRxiv. 2023. PMID: 36945474 Free PMC article. Updated. Preprint.
Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses.
Houston R, Sekine S, Calderon MJ, Seifuddin F, Wang G, Kawagishi H, Malide DA, Li Y, Gucek M, Pirooznia M, Nelson AJ, Stokes MP, Stewart-Ornstein J, Mullett SJ, Wendell SG, Watkins SC, Finkel T, Sekine Y. Houston R, et al. Among authors: stokes mp. PLoS Biol. 2020 Nov 30;18(11):e3000981. doi: 10.1371/journal.pbio.3000981. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33253182 Free PMC article.
43 results