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A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Maruggi G, Mallett CP, Westerbeck JW, Chen T, Lofano G, Friedrich K, Qu L, Sun JT, McAuliffe J, Kanitkar A, Arrildt KT, Wang KF, McBee I, McCoy D, Terry R, Rowles A, Abrahim MA, Ringenberg MA, Gains MJ, Spickler C, Xie X, Zou J, Shi PY, Dutt T, Henao-Tamayo M, Ragan I, Bowen RA, Johnson R, Nuti S, Luisi K, Ulmer JB, Steff AM, Jalah R, Bertholet S, Stokes AH, Yu D. Maruggi G, et al. Among authors: stokes ah. Mol Ther. 2022 May 4;30(5):1897-1912. doi: 10.1016/j.ymthe.2022.01.001. Epub 2022 Jan 3. Mol Ther. 2022. PMID: 34990810 Free PMC article. Clinical Trial.
Repeated Dose Toxicity Study and Developmental and Reproductive Toxicology Studies of a Respiratory Syncytial Virus Candidate Vaccine in Rabbits and Rats.
Stokes AH, Franklin K, Fisher DE, Posobiec LM, Binazon O, Tripathi N, Ringenberg MA, Charlap J, Ziejewski MK, Vemireddi V, Khanna Weiss P, Majumdar R, Bouzya B, Donner MN, Rodriguez LA, Baumeister J. Stokes AH, et al. Int J Toxicol. 2021 Mar-Apr;40(2):125-142. doi: 10.1177/1091581820985782. Epub 2021 Feb 1. Int J Toxicol. 2021. PMID: 33517807
Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats.
Stokes AH, Planty C, Pion J, Ancian P, Rogue A, Bansard C, Silvano J, Papineau D, Ben Abdeljelil N, Maruggi G, Song H, Spickler C, Blouin K, Dubois G, Rodriguez LA, Baumeister J, Steff AM, Destexhe E. Stokes AH, et al. Int J Toxicol. 2022 Aug;41(4):263-275. doi: 10.1177/10915818221101788. Epub 2022 Jun 2. Int J Toxicol. 2022. PMID: 35653115
MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats.
Madi S, Xie F, Farhangi K, Hsu CY, Cheng SH, Aweda T, Radaram B, Slania S, Lambert T, Rambo M, Skedzielewski T, Cole A, Sherina V, McKearnan S, Tran H, Alsaid H, Doan M, Stokes AH, O'Hagan DT, Maruggi G, Bertholet S, Temmerman ST, Johnson R, Jucker BM. Madi S, et al. Among authors: stokes ah. Front Immunol. 2023 Jan 11;13:1081156. doi: 10.3389/fimmu.2022.1081156. eCollection 2022. Front Immunol. 2023. PMID: 36713458 Free PMC article.
27 results