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A non-proteolytic release mechanism for HMCES-DNA-protein crosslinks.
Donsbach M, Dürauer S, Grünert F, Nguyen KT, Nigam R, Yaneva D, Weickert P, Bezalel-Buch R, Semlow DR, Stingele J. Donsbach M, et al. Among authors: stingele j. EMBO J. 2023 Sep 18;42(18):e113360. doi: 10.15252/embj.2022113360. Epub 2023 Jul 31. EMBO J. 2023. PMID: 37519246 Free PMC article.
Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.
Carnie CJ, Acampora AC, Bader AS, Erdenebat C, Zhao S, Bitensky E, van den Heuvel D, Parnas A, Gupta V, D'Alessandro G, Sczaniecka-Clift M, Weickert P, Aygenli F, Götz MJ, Cordes J, Esain-Garcia I, Melidis L, Wondergem AP, Lam S, Robles MS, Balasubramanian S, Adar S, Luijsterburg MS, Jackson SP, Stingele J. Carnie CJ, et al. Among authors: stingele j. Nat Cell Biol. 2024 May;26(5):797-810. doi: 10.1038/s41556-024-01391-1. Epub 2024 Apr 10. Nat Cell Biol. 2024. PMID: 38600235 Free PMC article.
Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS.
Carnie CJ, Götz MJ, Palma-Chaundler CS, Weickert P, Wanders A, Serrano-Benitez A, Li HY, Gupta V, Awwad SW, Blum CJ, Sczaniecka-Clift M, Cordes J, Zagnoli-Vieira G, D'Alessandro G, Richards SL, Gueorguieva N, Lam S, Beli P, Stingele J, Jackson SP. Carnie CJ, et al. Among authors: stingele j. EMBO J. 2024 May 17. doi: 10.1038/s44318-024-00108-2. Online ahead of print. EMBO J. 2024. PMID: 38760575 Free article.
RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks.
Zhao S, Cordes J, Caban KM, Götz MJ, Mackens-Kiani T, Veltri AJ, Sinha NK, Weickert P, Kaya S, Hewitt G, Nedialkova DD, Fröhlich T, Beckmann R, Buskirk AR, Green R, Stingele J. Zhao S, et al. Among authors: stingele j. Mol Cell. 2023 Dec 7;83(23):4290-4303.e9. doi: 10.1016/j.molcel.2023.10.012. Epub 2023 Nov 10. Mol Cell. 2023. PMID: 37951216 Free PMC article.
DNA-Protein Crosslinks and Their Resolution.
Weickert P, Stingele J. Weickert P, et al. Among authors: stingele j. Annu Rev Biochem. 2022 Jun 21;91:157-181. doi: 10.1146/annurev-biochem-032620-105820. Epub 2022 Mar 18. Annu Rev Biochem. 2022. PMID: 35303790 Review.
22 results