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Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer.
Sarode P, Zheng X, Giotopoulou GA, Weigert A, Kuenne C, Günther S, Friedrich A, Gattenlöhner S, Stiewe T, Brüne B, Grimminger F, Stathopoulos GT, Pullamsetti SS, Seeger W, Savai R. Sarode P, et al. Among authors: stiewe t. Sci Adv. 2020 Jun 5;6(23):eaaz6105. doi: 10.1126/sciadv.aaz6105. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32548260 Free PMC article.
Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma.
Banat GA, Tretyn A, Pullamsetti SS, Wilhelm J, Weigert A, Olesch C, Ebel K, Stiewe T, Grimminger F, Seeger W, Fink L, Savai R. Banat GA, et al. Among authors: stiewe t. PLoS One. 2015 Sep 28;10(9):e0139073. doi: 10.1371/journal.pone.0139073. eCollection 2015. PLoS One. 2015. PMID: 26413839 Free PMC article.
CRISPR-Cas9-based target validation for p53-reactivating model compounds.
Wanzel M, Vischedyk JB, Gittler MP, Gremke N, Seiz JR, Hefter M, Noack M, Savai R, Mernberger M, Charles JP, Schneikert J, Bretz AC, Nist A, Stiewe T. Wanzel M, et al. Among authors: stiewe t. Nat Chem Biol. 2016 Jan;12(1):22-8. doi: 10.1038/nchembio.1965. Epub 2015 Nov 23. Nat Chem Biol. 2016. PMID: 26595461 Free PMC article.
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses.
Timofeev O, Klimovich B, Schneikert J, Wanzel M, Pavlakis E, Noll J, Mutlu S, Elmshäuser S, Nist A, Mernberger M, Lamp B, Wenig U, Brobeil A, Gattenlöhner S, Köhler K, Stiewe T. Timofeev O, et al. Among authors: stiewe t. EMBO J. 2019 Oct 15;38(20):e102096. doi: 10.15252/embj.2019102096. Epub 2019 Sep 4. EMBO J. 2019. PMID: 31483066 Free PMC article.
Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion.
Ojasalu K, Brehm C, Hartung K, Nischak M, Finkernagel F, Rexin P, Nist A, Pavlakis E, Stiewe T, Jansen JM, Wagner U, Gattenlöhner S, Bräuninger A, Müller-Brüsselbach S, Reinartz S, Müller R. Ojasalu K, et al. Among authors: stiewe t. Mol Oncol. 2020 Sep;14(9):2142-2162. doi: 10.1002/1878-0261.12749. Epub 2020 Jun 25. Mol Oncol. 2020. PMID: 32533757 Free PMC article.
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures.
Hammoud MK, Dietze R, Pesek J, Finkernagel F, Unger A, Bieringer T, Nist A, Stiewe T, Bhagwat AM, Nockher WA, Reinartz S, Müller-Brüsselbach S, Graumann J, Müller R. Hammoud MK, et al. Among authors: stiewe t. Mol Oncol. 2022 Sep;16(17):3146-3166. doi: 10.1002/1878-0261.13221. Epub 2022 May 4. Mol Oncol. 2022. PMID: 35451191 Free PMC article.
149 results