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Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D. Gupta U, et al. Among authors: stepicheva na. Autophagy. 2023 Jan;19(1):92-111. doi: 10.1080/15548627.2022.2062887. Epub 2022 Apr 26. Autophagy. 2023. PMID: 35473441 Free PMC article.
Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.
Ghosh S, Padmanabhan A, Vaidya T, Watson AM, Bhutto IA, Hose S, Shang P, Stepicheva N, Yazdankhah M, Weiss J, Das M, Gopikrishna S, Aishwarya, Yadav N, Berger T, Mak TW, Xia S, Qian J, Lutty GA, Jayagopal A, Zigler JS Jr, Sethu S, Handa JT, Watkins SC, Ghosh A, Sinha D. Ghosh S, et al. Commun Biol. 2019 Sep 20;2:348. doi: 10.1038/s42003-019-0588-y. eCollection 2019. Commun Biol. 2019. PMID: 31552301 Free PMC article.
The role of lipocalin-2 in age-related macular degeneration (AMD).
Ghosh S, Stepicheva N, Yazdankhah M, Shang P, Watson AM, Hose S, Liu H, Weiss J, Zigler JS Jr, Valapala M, Watkins SC, Sinha D. Ghosh S, et al. Cell Mol Life Sci. 2020 Mar;77(5):835-851. doi: 10.1007/s00018-019-03423-8. Epub 2020 Jan 4. Cell Mol Life Sci. 2020. PMID: 31901947 Free PMC article. Review.
Role of glia in optic nerve.
Yazdankhah M, Shang P, Ghosh S, Hose S, Liu H, Weiss J, Fitting CS, Bhutto IA, Zigler JS Jr, Qian J, Sahel JA, Sinha D, Stepicheva NA. Yazdankhah M, et al. Among authors: stepicheva na. Prog Retin Eye Res. 2021 Mar;81:100886. doi: 10.1016/j.preteyeres.2020.100886. Epub 2020 Aug 6. Prog Retin Eye Res. 2021. PMID: 32771538 Free PMC article. Review.
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, Chamling X, Tian S, Sullivan MLG, Calderon MJ, Fitting CS, Weiss J, Jayagopal A, Handa JT, Sahel JA, Zigler JS Jr, Kinchington PR, Zack DJ, Sinha D. Yazdankhah M, et al. Autophagy. 2021 Oct;17(10):3140-3159. doi: 10.1080/15548627.2020.1871204. Epub 2021 Jan 19. Autophagy. 2021. PMID: 33404293 Free PMC article.
βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.
Ghosh S, Liu H, Yazdankhah M, Stepicheva N, Shang P, Vaidya T, Hose S, Gupta U, Calderon MJ, Hu MW, Nair AP, Weiss J, Fitting CS, Bhutto IA, Gadde SGK, Naik NK, Jaydev C, Lutty GA, Handa JT, Jayagopal A, Qian J, Sahel JA, Rajasundaram D, Sergeev Y, Zigler JS Jr, Sethu S, Watkins S, Ghosh A, Sinha D. Ghosh S, et al. Commun Biol. 2021 Feb 24;4(1):248. doi: 10.1038/s42003-021-01763-5. Commun Biol. 2021. PMID: 33627831 Free PMC article.
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