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Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Liang WC, Xi H, Sun D, D'Ascenzo L, Zarzar J, Stephens N, Cook R, Li Y, Ye Z, Matsumoto M, Payandeh J, Masureel M, Wu Y. Liang WC, et al. Among authors: stephens n. MAbs. 2024 Jan-Dec;16(1):2309685. doi: 10.1080/19420862.2024.2309685. Epub 2024 Feb 14. MAbs. 2024. PMID: 38356181 Free PMC article.
Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics.
Chu PY, Wang H, Ross E, Stephens N, Zhang HM, Andersen N, Chan W, Shivva V, Crowell SR, Spiess C, Holder PG, Agard NJ, Ji C, Chen J, Sreedhara A, Wang J, Wu C, Liu Y, Tran JC. Chu PY, et al. Among authors: stephens n. Anal Chem. 2023 Dec 12;95(49):17957-17961. doi: 10.1021/acs.analchem.3c02133. Epub 2023 Nov 30. Anal Chem. 2023. PMID: 38084380
Contrasting Health Outcomes following a Severe Smoke Episode and Ambient Air Pollution in Early Life: Findings from an Australian Data Linkage Cohort Study of Hospital Utilization.
Ziou M, Gao CX, Wheeler AJ, Zosky GR, Stephens N, Knibbs LD, Melody SM, Venn AJ, Dalton MF, Dharmage SC, Johnston FH. Ziou M, et al. Among authors: stephens n. Environ Health Perspect. 2023 Nov;131(11):117005. doi: 10.1289/EHP12238. Epub 2023 Nov 14. Environ Health Perspect. 2023. PMID: 37962441 Free PMC article.
528 results