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Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.
Stepanov AV, Xie J, Zhu Q, Shen Z, Su W, Kuai L, Soll R, Rader C, Shaver G, Douthit L, Zhang D, Kalinin R, Fu X, Zhao Y, Qin T, Baran PS, Gabibov AG, Bushnell D, Neri D, Kornberg RD, Lerner RA. Stepanov AV, et al. Nat Biomed Eng. 2023 Oct 5. doi: 10.1038/s41551-023-01102-5. Online ahead of print. Nat Biomed Eng. 2023. PMID: 37798444
Design of targeted B cell killing agents.
Stepanov AV, Belogurov AA Jr, Ponomarenko NA, Stremovskiy OA, Kozlov LV, Bichucher AM, Dmitriev SE, Smirnov IV, Shamborant OG, Balabashin DS, Sashchenko LP, Tonevitsky AG, Friboulet A, Gabibov AG, Deyev SM. Stepanov AV, et al. PLoS One. 2011;6(6):e20991. doi: 10.1371/journal.pone.0020991. Epub 2011 Jun 6. PLoS One. 2011. PMID: 21677771 Free PMC article.
Liposome-encapsulated peptides protect against experimental allergic encephalitis.
Belogurov AA Jr, Stepanov AV, Smirnov IV, Melamed D, Bacon A, Mamedov AE, Boitsov VM, Sashchenko LP, Ponomarenko NA, Sharanova SN, Boyko AN, Dubina MV, Friboulet A, Genkin DD, Gabibov AG. Belogurov AA Jr, et al. Among authors: stepanov av. FASEB J. 2013 Jan;27(1):222-31. doi: 10.1096/fj.12-213975. Epub 2012 Oct 9. FASEB J. 2013. PMID: 23047895 Free PMC article.
Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting.
Stepanov AV, Belogurov AA Jr, Kothapalli P, Shamborant OG, Knorre VD, Telegin GB, Ovsepyan AA, Ponomarenko NA, Deyev SM, Kaveri SV, Gabibov AG. Stepanov AV, et al. Acta Naturae. 2015 Apr-Jun;7(2):74-9. Acta Naturae. 2015. PMID: 26085947 Free PMC article.
Peptides Against Autoimmune Neurodegeneration.
Stepanov A, Lomakin Y, Gabibov A, Belogurov A. Stepanov A, et al. Curr Med Chem. 2017;24(17):1761-1771. doi: 10.2174/0929867324666170605092221. Curr Med Chem. 2017. PMID: 28578649 Review.
Death Receptors: New Opportunities in Cancer Therapy.
Ukrainskaya VM, Stepanov AV, Glagoleva IS, Knorre VD, Belogurov AAJ, Gabibov AG. Ukrainskaya VM, et al. Among authors: stepanov av. Acta Naturae. 2017 Jul-Sep;9(3):55-63. Acta Naturae. 2017. PMID: 29104776 Free PMC article.
Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.
Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J. Merkouris S, et al. Among authors: stepanov av. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7023-E7032. doi: 10.1073/pnas.1806660115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987039 Free PMC article.
Directed Change in TNFα Specificity to Create DR5 Antagonists.
Ukrainskaya VM, Bobik TV, Argentova-Stevens A, Slutskaya EA, Kalinin RS, Gabibov AG, Stepanov AV. Ukrainskaya VM, et al. Among authors: stepanov av. Bull Exp Biol Med. 2018 Jul;165(3):386-389. doi: 10.1007/s10517-018-4176-9. Epub 2018 Jul 12. Bull Exp Biol Med. 2018. PMID: 30003423
152 results