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The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells.
Pflüger-Müller B, Oo JA, Heering J, Warwick T, Proschak E, Günther S, Looso M, Rezende F, Fork C, Geisslinger G, Thomas D, Gurke R, Steinhilber D, Schulz M, Leisegang MS, Brandes RP. Pflüger-Müller B, et al. Among authors: steinhilber d. Basic Res Cardiol. 2020 Apr 22;115(3):34. doi: 10.1007/s00395-020-0793-3. Basic Res Cardiol. 2020. PMID: 32323032 Free PMC article.
Intracellular localization of RORalpha is isoform and cell line-dependent.
Aschrafi A, Meindl N, Firla B, Brandes RP, Steinhilber D. Aschrafi A, et al. Among authors: steinhilber d. Biochim Biophys Acta. 2006 Aug;1763(8):805-14. doi: 10.1016/j.bbamcr.2006.05.006. Epub 2006 May 17. Biochim Biophys Acta. 2006. PMID: 16806533 Free article.
Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro.
Lechtken A, Hörnig M, Werz O, Corvey N, Zündorf I, Dingermann T, Brandes R, Steinhilber D. Lechtken A, et al. Among authors: steinhilber d. Biochem Biophys Res Commun. 2007 Jul 6;358(3):890-6. doi: 10.1016/j.bbrc.2007.05.016. Epub 2007 May 11. Biochem Biophys Res Commun. 2007. PMID: 17512500
Scaffold-hopping cascade yields potent inhibitors of 5-lipoxygenase.
Hofmann B, Franke L, Proschak E, Tanrikulu Y, Schneider P, Steinhilber D, Schneider G. Hofmann B, et al. Among authors: steinhilber d. ChemMedChem. 2008 Oct;3(10):1535-8. doi: 10.1002/cmdc.200800153. ChemMedChem. 2008. PMID: 18688907 No abstract available.
Celecoxib inhibits 5-lipoxygenase.
Maier TJ, Tausch L, Hoernig M, Coste O, Schmidt R, Angioni C, Metzner J, Groesch S, Pergola C, Steinhilber D, Werz O, Geisslinger G. Maier TJ, et al. Among authors: steinhilber d. Biochem Pharmacol. 2008 Oct 1;76(7):862-72. doi: 10.1016/j.bcp.2008.07.009. Epub 2008 Jul 19. Biochem Pharmacol. 2008. PMID: 18692027
PhAST: pharmacophore alignment search tool.
Hähnke V, Hofmann B, Grgat T, Proschak E, Steinhilber D, Schneider G. Hähnke V, et al. Among authors: steinhilber d. J Comput Chem. 2009 Apr 15;30(5):761-71. doi: 10.1002/jcc.21095. J Comput Chem. 2009. PMID: 18727161
Cellular membranes function as a storage compartment for celecoxib.
Maier TJ, Schiffmann S, Wobst I, Birod K, Angioni C, Hoffmann M, Lopez JJ, Glaubitz C, Steinhilber D, Geisslinger G, Grösch S. Maier TJ, et al. Among authors: steinhilber d. J Mol Med (Berl). 2009 Oct;87(10):981-93. doi: 10.1007/s00109-009-0506-8. Epub 2009 Jul 30. J Mol Med (Berl). 2009. PMID: 19641861
Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.
Steinbrink SD, Pergola C, Bühring U, George S, Metzner J, Fischer AS, Häfner AK, Wisniewska JM, Geisslinger G, Werz O, Steinhilber D, Maier TJ. Steinbrink SD, et al. Among authors: steinhilber d. Cell Mol Life Sci. 2010 Mar;67(5):797-806. doi: 10.1007/s00018-009-0206-0. Epub 2009 Nov 29. Cell Mol Life Sci. 2010. PMID: 20091083
305 results