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A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders.
Detera-Wadleigh SD, Kassem L, Besancon E, Lopes F, Akula N, Sung H, Blattner M, Sheridan L, Lacbawan LN, Garcia J, Gordovez F, Hosey K, Donner C, Salvini C, Schulze T, Chen DTW, England B, Cross J, Jiang X, Corona W, Russ J, Mallon B, Dutra A, Pak E, Steiner J, Malik N, de Guzman T, Horato N, Mallmann MB, Mendes V, Dűck AL, Nardi AE, McMahon FJ. Detera-Wadleigh SD, et al. Among authors: steiner j. Transl Psychiatry. 2023 Dec 16;13(1):397. doi: 10.1038/s41398-023-02641-w. Transl Psychiatry. 2023. PMID: 38104115 Free PMC article.
Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling.
Efthymiou AG, Steiner J, Pavan WJ, Wincovitch S, Larson DM, Porter FD, Rao MS, Malik N. Efthymiou AG, et al. Among authors: steiner j. Stem Cells Transl Med. 2015 Mar;4(3):230-8. doi: 10.5966/sctm.2014-0127. Epub 2015 Jan 30. Stem Cells Transl Med. 2015. PMID: 25637190 Free PMC article.
Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway.
Wang T, Medynets M, Johnson KR, Doucet-O'Hare TT, DiSanza B, Li W, Xu Y, Bagnell A, Tyagi R, Sampson K, Malik N, Steiner J, Hadegan A, Kowalak J, O'Malley J, Maric D, Nath A. Wang T, et al. Among authors: steiner j. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17842-17853. doi: 10.1073/pnas.2002427117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669437 Free PMC article.
Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor.
Toodle V, Lee MH, Bachani M, Ruffin A, Vivekanandhan S, Malik N, Wang T, Johnson TP, Nath A, Steiner JP. Toodle V, et al. Neurotherapeutics. 2022 Jul;19(4):1313-1328. doi: 10.1007/s13311-022-01265-0. Epub 2022 Jul 13. Neurotherapeutics. 2022. PMID: 35831747 Free PMC article.
Neurotoxic properties of the Zika virus envelope protein.
Steiner JP, Bachani M, Malik N, Li W, Tyagi R, Sampson K, Abrams RPM, Kousa Y, Solis J, Johnson TP, Nath A. Steiner JP, et al. Exp Neurol. 2023 Sep;367:114469. doi: 10.1016/j.expneurol.2023.114469. Epub 2023 Jun 14. Exp Neurol. 2023. PMID: 37327963
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Abrams RPM, Yasgar A, Teramoto T, Lee MH, Dorjsuren D, Eastman RT, Malik N, Zakharov AV, Li W, Bachani M, Brimacombe K, Steiner JP, Hall MD, Balasubramanian A, Jadhav A, Padmanabhan R, Simeonov A, Nath A. Abrams RPM, et al. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31365-31375. doi: 10.1073/pnas.2005463117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229545 Free PMC article.
Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic.
Steiner JP, Bachani M, Malik N, DeMarino C, Li W, Sampson K, Lee MH, Kowalak J, Bhaskar M, Doucet-O'Hare T, Garcia-Montojo M, Cowen M, Smith B, Reoma LB, Medina J, Brunel J, Pierquin J, Charvet B, Perron H, Nath A. Steiner JP, et al. Ann Neurol. 2022 Oct;92(4):545-561. doi: 10.1002/ana.26452. Epub 2022 Jul 30. Ann Neurol. 2022. PMID: 35801347 Free PMC article.
1,944 results