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Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S. Petzold T, et al. Among authors: stegner d. Immunity. 2022 Dec 13;55(12):2285-2299.e7. doi: 10.1016/j.immuni.2022.10.001. Epub 2022 Oct 21. Immunity. 2022. PMID: 36272416 Free PMC article.
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.
Drube S, Weber F, Loschinski R, Beyer M, Rothe M, Rabenhorst A, Göpfert C, Meininger I, Diamanti MA, Stegner D, Häfner N, Böttcher M, Reinecke K, Herdegen T, Greten FR, Nieswandt B, Hartmann K, Krämer OH, Kamradt T. Drube S, et al. Among authors: stegner d. Oncotarget. 2015 Mar 10;6(7):5354-68. doi: 10.18632/oncotarget.3022. Oncotarget. 2015. PMID: 25749030 Free PMC article.
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear.
Perrella G, Montague SJ, Brown HC, Garcia Quintanilla L, Slater A, Stegner D, Thomas M, Heemskerk JWM, Watson SP. Perrella G, et al. Among authors: stegner d. Int J Mol Sci. 2022 Jan 1;23(1):493. doi: 10.3390/ijms23010493. Int J Mol Sci. 2022. PMID: 35008919 Free PMC article.
Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.
Deppermann C, Cherpokova D, Nurden P, Schulz JN, Thielmann I, Kraft P, Vögtle T, Kleinschnitz C, Dütting S, Krohne G, Eming SA, Nurden AT, Eckes B, Stoll G, Stegner D, Nieswandt B. Deppermann C, et al. Among authors: stegner d. J Clin Invest. 2013 Jul 1;123(8):3331-42. doi: 10.1172/JCI69210. Online ahead of print. J Clin Invest. 2013. PMID: 23863626 Free PMC article.
104 results