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Perspectives of data science in preclinical safety assessment.
Steger-Hartmann T, Kreuchwig A, Wang K, Birzele F, Draganov D, Gaudio S, Rothfuss A. Steger-Hartmann T, et al. Drug Discov Today. 2023 Aug;28(8):103642. doi: 10.1016/j.drudis.2023.103642. Epub 2023 May 26. Drug Discov Today. 2023. PMID: 37244565 Review.
Legacy data sharing to improve drug safety assessment: the eTOX project.
Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX; Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Sanz F, et al. Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13. Nat Rev Drug Discov. 2017. PMID: 29026211 Free article.
The evolving role of investigative toxicology in the pharmaceutical industry.
Pognan F, Beilmann M, Boonen HCM, Czich A, Dear G, Hewitt P, Mow T, Oinonen T, Roth A, Steger-Hartmann T, Valentin JP, Van Goethem F, Weaver RJ, Newham P. Pognan F, et al. Among authors: steger hartmann t. Nat Rev Drug Discov. 2023 Apr;22(4):317-335. doi: 10.1038/s41573-022-00633-x. Epub 2023 Feb 13. Nat Rev Drug Discov. 2023. PMID: 36781957 Free PMC article. Review.
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives.
Pognan F, Steger-Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K, Callegaro G, Capella-Gutierrez S, Centeno E, Corvi J, Drew P, Drewe WC, Fernández JM, Furlong LI, Guney E, Kors JA, Mayer MA, Pastor M, Piñero J, Ramírez-Anguita JM, Ronzano F, Rowell P, Saüch-Pitarch J, Valencia A, van de Water B, van der Lei J, van Mulligen E, Sanz F. Pognan F, et al. Pharmaceuticals (Basel). 2021 Mar 8;14(3):237. doi: 10.3390/ph14030237. Pharmaceuticals (Basel). 2021. PMID: 33800393 Free PMC article.
61 results