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PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System.
Boltnarova B, Kubackova J, Skoda J, Stefela A, Smekalova M, Svacinova P, Pavkova I, Dittrich M, Scherman D, Zbytovska J, Pavek P, Holas O. Boltnarova B, et al. Among authors: stefela a. Nanomaterials (Basel). 2021 Mar 16;11(3):749. doi: 10.3390/nano11030749. Nanomaterials (Basel). 2021. PMID: 33809764 Free PMC article.
(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells.
Stefela A, Kaspar M, Drastik M, Kronenberger T, Micuda S, Dracinsky M, Klepetarova B, Kudova E, Pavek P. Stefela A, et al. Front Pharmacol. 2021 Aug 13;12:713149. doi: 10.3389/fphar.2021.713149. eCollection 2021. Front Pharmacol. 2021. PMID: 34483922 Free PMC article.
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis.
Lastuvkova H, Nova Z, Hroch M, Alaei Faradonbeh F, Schreiberova J, Mokry J, Faistova H, Stefela A, Dusek J, Kucera O, Hyspler R, Dohnalkova E, Bayer RL, Hirsova P, Pavek P, Micuda S. Lastuvkova H, et al. Among authors: stefela a. Toxicol Sci. 2023 Nov 28;196(2):200-217. doi: 10.1093/toxsci/kfad088. Toxicol Sci. 2023. PMID: 37632784 Free PMC article.
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Mejdrová I, Dušek J, Škach K, Stefela A, Skoda J, Chalupský K, Dohnalová K, Pavkova I, Kronenberger T, Rashidian A, Smutná L, Duchoslav V, Smutny T, Pávek P, Nencka R. Mejdrová I, et al. Among authors: stefela a. J Med Chem. 2023 Feb 23;66(4):2422-2456. doi: 10.1021/acs.jmedchem.2c01140. Epub 2023 Feb 9. J Med Chem. 2023. PMID: 36756805 Free PMC article.