Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
8 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System.
Nanomaterials (Basel). 2021 Mar 16;11(3):749. doi: 10.3390/nano11030749.
Nanomaterials (Basel). 2021.
PMID: 33809764
Free PMC article.
3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism.
Stefela A, Kaspar M, Drastik M, Holas O, Hroch M, Smutny T, Skoda J, Hutníková M, Pandey AV, Micuda S, Kudova E, Pavek P.
Stefela A, et al.
J Steroid Biochem Mol Biol. 2020 Sep;202:105702. doi: 10.1016/j.jsbmb.2020.105702. Epub 2020 Jun 4.
J Steroid Biochem Mol Biol. 2020.
PMID: 32505574
Item in Clipboard
Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain.
Skoda J, Dusek J, Drastik M, Stefela A, Dohnalova K, Chalupsky K, Smutny T, Micuda S, Gerbal-Chaloin S, Pavek P.
Skoda J, et al. Among authors: stefela a.
Cells. 2020 Nov 24;9(12):2532. doi: 10.3390/cells9122532.
Cells. 2020.
PMID: 33255185
Free PMC article.
Item in Clipboard
(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells.
Stefela A, Kaspar M, Drastik M, Kronenberger T, Micuda S, Dracinsky M, Klepetarova B, Kudova E, Pavek P.
Stefela A, et al.
Front Pharmacol. 2021 Aug 13;12:713149. doi: 10.3389/fphar.2021.713149. eCollection 2021.
Front Pharmacol. 2021.
PMID: 34483922
Free PMC article.
Item in Clipboard
Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis.
Lastuvkova H, Faradonbeh FA, Schreiberova J, Hroch M, Mokry J, Faistova H, Nova Z, Hyspler R, Igreja Sa IC, Nachtigal P, Stefela A, Pavek P, Micuda S.
Lastuvkova H, et al. Among authors: stefela a.
Int J Mol Sci. 2021 Jun 16;22(12):6468. doi: 10.3390/ijms22126468.
Int J Mol Sci. 2021.
PMID: 34208774
Free PMC article.
Item in Clipboard
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis.
Lastuvkova H, Nova Z, Hroch M, Alaei Faradonbeh F, Schreiberova J, Mokry J, Faistova H, Stefela A, Dusek J, Kucera O, Hyspler R, Dohnalkova E, Bayer RL, Hirsova P, Pavek P, Micuda S.
Lastuvkova H, et al. Among authors: stefela a.
Toxicol Sci. 2023 Nov 28;196(2):200-217. doi: 10.1093/toxsci/kfad088.
Toxicol Sci. 2023.
PMID: 37632784
Free PMC article.
Item in Clipboard
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Mejdrová I, Dušek J, Škach K, Stefela A, Skoda J, Chalupský K, Dohnalová K, Pavkova I, Kronenberger T, Rashidian A, Smutná L, Duchoslav V, Smutny T, Pávek P, Nencka R.
Mejdrová I, et al. Among authors: stefela a.
J Med Chem. 2023 Feb 23;66(4):2422-2456. doi: 10.1021/acs.jmedchem.2c01140. Epub 2023 Feb 9.
J Med Chem. 2023.
PMID: 36756805
Free PMC article.
Item in Clipboard
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists.
Díaz-Holguín A, Rashidian A, Pijnenburg D, Monteiro Ferreira G, Stefela A, Kaspar M, Kudova E, Poso A, van Beuningen R, Pavek P, Kronenberger T.
Díaz-Holguín A, et al. Among authors: stefela a.
ChemMedChem. 2023 Feb 14;18(4):e202200556. doi: 10.1002/cmdc.202200556. Epub 2022 Nov 30.
ChemMedChem. 2023.
PMID: 36398403
Item in Clipboard
Cite
Cite