Staschke KA - Search Results

1

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis.

Cordova RA, Misra J, Amin PH, Klunk AJ, Damayanti NP, Carlson KR, Elmendorf AJ, Kim HG, Mirek ET, Elzey BD, Miller MJ, Dong XC, Cheng L, Anthony TG, Pili R, Wek RC, Staschke KA. Cordova RA, et al. Among authors: staschke ka. Elife. 2022 Sep 15;11:e81083. doi: 10.7554/eLife.81083. Elife. 2022. PMID: 36107759 Free PMC article.

2

Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha).

Vattem KM, Staschke KA, Zhu S, Wek RC. Vattem KM, et al. Among authors: staschke ka. Eur J Biochem. 2001 Feb;268(4):1143-53. doi: 10.1046/j.1432-1327.2001.01979.x. Eur J Biochem. 2001. PMID: 11179981 Free article.

3

Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).

Vattem KM, Staschke KA, Wek RC. Vattem KM, et al. Among authors: staschke ka. Eur J Biochem. 2001 Jul;268(13):3674-84. doi: 10.1046/j.1432-1327.2001.02273.x. Eur J Biochem. 2001. PMID: 11432733 Free article.

4

Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions.

Narasimhan J, Staschke KA, Wek RC. Narasimhan J, et al. Among authors: staschke ka. J Biol Chem. 2004 May 28;279(22):22820-32. doi: 10.1074/jbc.M402228200. Epub 2004 Mar 9. J Biol Chem. 2004. PMID: 15010461 Free article.

5

Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions.

Zhou D, Palam LR, Jiang L, Narasimhan J, Staschke KA, Wek RC. Zhou D, et al. Among authors: staschke ka. J Biol Chem. 2008 Mar 14;283(11):7064-73. doi: 10.1074/jbc.M708530200. Epub 2008 Jan 14. J Biol Chem. 2008. PMID: 18195013 Free article.

6

Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast.

Staschke KA, Dey S, Zaborske JM, Palam LR, McClintick JN, Pan T, Edenberg HJ, Wek RC. Staschke KA, et al. J Biol Chem. 2010 May 28;285(22):16893-911. doi: 10.1074/jbc.M110.121947. Epub 2010 Mar 16. J Biol Chem. 2010. PMID: 20233714 Free PMC article.

7

How do tumours adapt to nutrient stress?

Wek RC, Staschke KA. Wek RC, et al. Among authors: staschke ka. EMBO J. 2010 Jun 16;29(12):1946-7. doi: 10.1038/emboj.2010.110. EMBO J. 2010. PMID: 20551969 Free PMC article. No abstract available.

8

Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii.

Augusto L, Martynowicz J, Staschke KA, Wek RC, Sullivan WJ Jr. Augusto L, et al. Among authors: staschke ka. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01442-18. doi: 10.1128/AAC.01442-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30181373 Free PMC article.

9

Adapting to cell stress from inside and out.

Staschke KA, Wek RC. Staschke KA, et al. Nat Cell Biol. 2019 Jul;21(7):799-800. doi: 10.1038/s41556-019-0354-x. Nat Cell Biol. 2019. PMID: 31263267 No abstract available.

10

Asparagine bioavailability regulates the translation of MYC oncogene.

Srivastava S, Jiang J, Misra J, Seim G, Staschke KA, Zhong M, Zhou L, Liu Y, Chen C, Davé U, Kapur R, Batra S, Zhang C, Zhou J, Fan J, Wek RC, Zhang J. Srivastava S, et al. Among authors: staschke ka. Oncogene. 2022 Oct;41(44):4855-4865. doi: 10.1038/s41388-022-02474-9. Epub 2022 Oct 1. Oncogene. 2022. PMID: 36182969 Free PMC article.

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