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Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.
McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, Geschwind DH, Ryu H, Xia L, Iismaa SE, Pallos J, Pasternack R, Hils M, Fan J, Raymond LA, Marsh JL, Thompson LM, Ratan RR. McConoughey SJ, et al. Among authors: starkov a. EMBO Mol Med. 2010 Sep;2(9):349-70. doi: 10.1002/emmm.201000084. EMBO Mol Med. 2010. PMID: 20665636 Free PMC article.
Impaired PGC-1alpha function in muscle in Huntington's disease.
Chaturvedi RK, Adhihetty P, Shukla S, Hennessy T, Calingasan N, Yang L, Starkov A, Kiaei M, Cannella M, Sassone J, Ciammola A, Squitieri F, Beal MF. Chaturvedi RK, et al. Among authors: starkov a. Hum Mol Genet. 2009 Aug 15;18(16):3048-65. doi: 10.1093/hmg/ddp243. Epub 2009 May 21. Hum Mol Genet. 2009. PMID: 19460884 Free PMC article.
Promethazine protects against 3-nitropropionic acid-induced neurotoxicity.
Cleren C, Calingasan NY, Starkov A, Jacquard C, Chen J, Brouillet E, Beal MF. Cleren C, et al. Among authors: starkov a. Neurochem Int. 2010 Jan;56(2):208-12. doi: 10.1016/j.neuint.2009.10.006. Epub 2009 Oct 21. Neurochem Int. 2010. PMID: 19852992 Free PMC article.
Mice lacking alpha-synuclein are resistant to mitochondrial toxins.
Klivenyi P, Siwek D, Gardian G, Yang L, Starkov A, Cleren C, Ferrante RJ, Kowall NW, Abeliovich A, Beal MF. Klivenyi P, et al. Among authors: starkov a. Neurobiol Dis. 2006 Mar;21(3):541-8. doi: 10.1016/j.nbd.2005.08.018. Epub 2005 Nov 18. Neurobiol Dis. 2006. PMID: 16298531
Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease.
Thomas B, Banerjee R, Starkova NN, Zhang SF, Calingasan NY, Yang L, Wille E, Lorenzo BJ, Ho DJ, Beal MF, Starkov A. Thomas B, et al. Among authors: starkov a. Antioxid Redox Signal. 2012 May 1;16(9):855-68. doi: 10.1089/ars.2010.3849. Epub 2011 Jun 16. Antioxid Redox Signal. 2012. PMID: 21529244 Free PMC article.
147 results