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Page 1
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Among authors: stahl ec. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus.
Ehrenberg AJ, Moehle EA, Brook CE, Doudna Cate AH, Witkowsky LB, Sachdeva R, Hirsh A, Barry K, Hamilton JR, Lin-Shiao E, McDevitt S, Valentin-Alvarado L, Letourneau KN, Hunter L, Keller A, Pestal K, Frankino PA, Murley A, Nandakumar D, Stahl EC, Tsuchida CA, Gildea HK, Murdock AG, Hochstrasser ML, O'Brien E, Ciling A, Tsitsiklis A, Worden K, Dugast-Darzacq C, Hays SG, Barber CC, McGarrigle R, Lam EK, Ensminger DC, Bardet L, Sherry C, Harte A, Nicolette G, Giannikopoulos P, Hockemeyer D, Petersen M, Urnov FD, Ringeisen BR, Boots M, Doudna JA; IGI SARS-CoV-2 Testing Consortium. Ehrenberg AJ, et al. Among authors: stahl ec. PLoS One. 2021 May 26;16(5):e0251296. doi: 10.1371/journal.pone.0251296. eCollection 2021. PLoS One. 2021. PMID: 34038425 Free PMC article.
Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples.
Hamilton JR, Stahl EC, Tsuchida CA, Lin-Shiao E, Tsui CK, Pestal K, Gildea HK, Witkowsky LB, Moehle EA, McDevitt SL, McElroy M, Keller A, Sylvain I, Hirsh A, Ciling A, Ehrenberg AJ, Ringeisen BR, Huberty G, Urnov FD, Giannikopoulos P, Doudna JA; IGI SARS-CoV-2 Consortium. Hamilton JR, et al. Among authors: stahl ec. PLoS One. 2021 Aug 5;16(8):e0255690. doi: 10.1371/journal.pone.0255690. eCollection 2021. PLoS One. 2021. PMID: 34351984 Free PMC article.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. Nat Chem Biol. 2021. PMID: 34354262 Free PMC article.
Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Nat Chem Biol. 2021 Nov;17(11):1210. doi: 10.1038/s41589-021-00882-8. Nat Chem Biol. 2021. PMID: 34616098 Free PMC article. No abstract available.
LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.
Stahl EC, Gopez AR, Tsuchida CA, Fan VB, Moehle EA, Witkowsky LB, Hamilton JR, Lin-Shiao E, McElroy M, McDevitt SL, Ciling A, Tsui CK, Pestal K, Gildea HK, Keller A, Sylvain IA, Williams C, Hirsh A, Ehrenberg AJ, Kantor R, Metzger M, Nelson KL, Urnov FD, Ringeisen BR, Giannikopoulos P, Doudna JA; IGI Testing Consortium. Stahl EC, et al. PLoS One. 2021 Nov 10;16(11):e0258263. doi: 10.1371/journal.pone.0258263. eCollection 2021. PLoS One. 2021. PMID: 34758033 Free PMC article.
CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.
Lin-Shiao E, Pfeifer WG, Shy BR, Saffari Doost M, Chen E, Vykunta VS, Hamilton JR, Stahl EC, Lopez DM, Sandoval Espinoza CR, Deyanov AE, Lew RJ, Poirer MG, Marson A, Castro CE, Doudna JA. Lin-Shiao E, et al. Among authors: stahl ec. Nucleic Acids Res. 2022 Feb 22;50(3):1256-1268. doi: 10.1093/nar/gkac049. Nucleic Acids Res. 2022. PMID: 35104875 Free PMC article.
Rapid detection of SARS-CoV-2 RNA in saliva via Cas13.
Chandrasekaran SS, Agrawal S, Fanton A, Jangid AR, Charrez B, Escajeda AM, Son S, Mcintosh R, Tran H, Bhuiya A, de León Derby MD, Switz NA, Armstrong M, Harris AR, Prywes N, Lukarska M, Biering SB, Smock DCJ, Mok A, Knott GJ, Dang Q, Van Dis E, Dugan E, Kim S, Liu TY; IGI Testing Consortium; Moehle EA, Kogut K, Eskenazi B, Harris E, Stanley SA, Lareau LF, Tan MX, Fletcher DA, Doudna JA, Savage DF, Hsu PD. Chandrasekaran SS, et al. Nat Biomed Eng. 2022 Aug;6(8):944-956. doi: 10.1038/s41551-022-00917-y. Epub 2022 Aug 11. Nat Biomed Eng. 2022. PMID: 35953650 Free PMC article.
Improved genome editing by an engineered CRISPR-Cas12a.
Ma E, Chen K, Shi H, Stahl EC, Adler B, Trinidad M, Liu J, Zhou K, Ye J, Doudna JA. Ma E, et al. Among authors: stahl ec. Nucleic Acids Res. 2022 Dec 9;50(22):12689-12701. doi: 10.1093/nar/gkac1192. Nucleic Acids Res. 2022. PMID: 36537251 Free PMC article.
Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs.
Stahl EC, Sabo JK, Kang MH, Allen R, Applegate E, Kim SE, Kwon Y, Seth A, Lemus N, Salinas-Rios V, Soczek KM, Trinidad M, Vo LT, Jeans C, Wozniak A, Morris T, Kimberlin A, Foti T, Savage DF, Doudna JA. Stahl EC, et al. Mol Ther. 2023 Aug 2;31(8):2422-2438. doi: 10.1016/j.ymthe.2023.06.019. Epub 2023 Jul 4. Mol Ther. 2023. PMID: 37403358 Free article.
27 results