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GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
Quarta C, Stemmer K, Novikoff A, Yang B, Klingelhuber F, Harger A, Bakhti M, Bastidas-Ponce A, Baugé E, Campbell JE, Capozzi M, Clemmensen C, Collden G, Cota P, Douros J, Drucker DJ, DuBois B, Feuchtinger A, Garcia-Caceres C, Grandl G, Hennuyer N, Herzig S, Hofmann SM, Knerr PJ, Kulaj K, Lalloyer F, Lickert H, Liskiewicz A, Liskiewicz D, Maity G, Perez-Tilve D, Prakash S, Sanchez-Garrido MA, Zhang Q, Staels B, Krahmer N, DiMarchi RD, Tschöp MH, Finan B, Müller TD. Quarta C, et al. Among authors: staels b. Nat Metab. 2022 Aug;4(8):1071-1083. doi: 10.1038/s42255-022-00617-6. Epub 2022 Aug 22. Nat Metab. 2022. PMID: 35995995 Free PMC article.
4,4-Dimethyl-1,2,3,4-tetrahydroquinoline-based PPARalpha/gamma agonists. Part. II: Synthesis and pharmacological evaluation of oxime and acidic head group structural variations.
Parmenon C, Guillard J, Caignard DH, Hennuyer N, Staels B, Audinot-Bouchez V, Boutin JA, Dacquet C, Ktorza A, Viaud-Massuard MC. Parmenon C, et al. Among authors: staels b. Bioorg Med Chem Lett. 2009 May 15;19(10):2683-7. doi: 10.1016/j.bmcl.2009.03.143. Epub 2009 Apr 1. Bioorg Med Chem Lett. 2009. PMID: 19376700
Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.
Lalloyer F, Pedersen TA, Gross B, Lestavel S, Yous S, Vallez E, Gustafsson JA, Mandrup S, Fiévet C, Staels B, Tailleux A. Lalloyer F, et al. Among authors: staels b. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1488-95. doi: 10.1161/ATVBAHA.109.189506. Epub 2009 Jul 10. Arterioscler Thromb Vasc Biol. 2009. PMID: 19592467 Free PMC article.
792 results