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STK25 is a critical determinant in nonalcoholic steatohepatitis.
Amrutkar M, Chursa U, Kern M, Nuñez-Durán E, Ståhlman M, Sütt S, Borén J, Johansson BR, Marschall HU, Blüher M, Mahlapuu M. Amrutkar M, et al. Among authors: stahlman m. FASEB J. 2016 Oct;30(10):3628-3643. doi: 10.1096/fj.201600562R. Epub 2016 Jul 15. FASEB J. 2016. PMID: 27421788
The study provides evidence for multiple roles of STK25 in NASH pathogenesis and future investigations to address the potential therapeutic relevance of pharmacological STK25 inhibitors in prevention and treatment of NASH are warranted.-Amrutkar, M., Chursa, U., Kern, M …
The study provides evidence for multiple roles of STK25 in NASH pathogenesis and future investigations to address the potential therapeutic …
Hypoxia converts human macrophages into triglyceride-loaded foam cells.
Boström P, Magnusson B, Svensson PA, Wiklund O, Borén J, Carlsson LM, Ståhlman M, Olofsson SO, Hultén LM. Boström P, et al. Among authors: stahlman m. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1871-6. doi: 10.1161/01.ATV.0000229665.78997.0b. Epub 2006 Jun 1. Arterioscler Thromb Vasc Biol. 2006. PMID: 16741148
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction.
Perman JC, Boström P, Lindbom M, Lidberg U, StÅhlman M, Hägg D, Lindskog H, Scharin Täng M, Omerovic E, Mattsson Hultén L, Jeppsson A, Petursson P, Herlitz J, Olivecrona G, Strickland DK, Ekroos K, Olofsson SO, Borén J. Perman JC, et al. Among authors: stahlman m. J Clin Invest. 2011 Jul;121(7):2625-40. doi: 10.1172/JCI43068. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670500 Free PMC article.
Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.
Levin MC, Jirholt P, Wramstedt A, Johansson ME, Lundberg AM, Trajkovska MG, Ståhlman M, Fogelstrand P, Brisslert M, Fogelstrand L, Yan ZQ, Hansson GK, Björkbacka H, Olofsson SO, Borén J. Levin MC, et al. Among authors: stahlman m. Circ Res. 2011 Nov 11;109(11):1210-8. doi: 10.1161/CIRCRESAHA.111.246702. Epub 2011 Sep 29. Circ Res. 2011. PMID: 21959219
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.
Pirazzi C, Adiels M, Burza MA, Mancina RM, Levin M, Ståhlman M, Taskinen MR, Orho-Melander M, Perman J, Pujia A, Andersson L, Maglio C, Montalcini T, Wiklund O, Borén J, Romeo S. Pirazzi C, et al. Among authors: stahlman m. J Hepatol. 2012 Dec;57(6):1276-82. doi: 10.1016/j.jhep.2012.07.030. Epub 2012 Aug 6. J Hepatol. 2012. PMID: 22878467
286 results