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Activating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade.
Yadavilli S, Waight JD, Brett S, Bi M, Zhang T, Liu YB, Ellis C, Turner DC, Hahn A, Shi H, Seestaller-Wehr L, Jing J, Xie Q, Shaik JS, Ji X, Gagnon R, Fieles W, Hook L, Grant S, Hopley S, DeYoung MP, Blackwell C, Chisamore M, Biddlecombe R, Figueroa DJ, Hopson CB, Srinivasan R, Smothers J, Maio M, Rischin D, Olive D, Paul E, Mayes PA, Hoos A, Ballas M. Yadavilli S, et al. Among authors: srinivasan r. Cancer Res Commun. 2023 Aug 16;3(8):1564-1579. doi: 10.1158/2767-9764.CRC-22-0293. eCollection 2023 Aug. Cancer Res Commun. 2023. PMID: 37593752 Free PMC article. Clinical Trial.
Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo.
Montes de Oca R, Alavi AS, Vitali N, Bhattacharya S, Blackwell C, Patel K, Seestaller-Wehr L, Kaczynski H, Shi H, Dobrzynski E, Obert L, Tsvetkov L, Cooper DC, Jackson H, Bojczuk P, Forveille S, Kepp O, Sauvat A, Kroemer G, Creighton-Gutteridge M, Yang J, Hopson C, Yanamandra N, Shelton C, Mayes P, Opalinska J, Barnette M, Srinivasan R, Smothers J, Hoos A. Montes de Oca R, et al. Among authors: srinivasan r. Mol Cancer Ther. 2021 Oct;20(10):1941-1955. doi: 10.1158/1535-7163.MCT-21-0035. Epub 2021 Jul 12. Mol Cancer Ther. 2021. PMID: 34253590 Free PMC article.
Big opportunities for small molecules in immuno-oncology.
Adams JL, Smothers J, Srinivasan R, Hoos A. Adams JL, et al. Among authors: srinivasan r. Nat Rev Drug Discov. 2015 Sep;14(9):603-22. doi: 10.1038/nrd4596. Epub 2015 Jul 31. Nat Rev Drug Discov. 2015. PMID: 26228631 Review.
Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments.
Yu JW, Bhattacharya S, Yanamandra N, Kilian D, Shi H, Yadavilli S, Katlinskaya Y, Kaczynski H, Conner M, Benson W, Hahn A, Seestaller-Wehr L, Bi M, Vitali NJ, Tsvetkov L, Halsey W, Hughes A, Traini C, Zhou H, Jing J, Lee T, Figueroa DJ, Brett S, Hopson CB, Smothers JF, Hoos A, Srinivasan R. Yu JW, et al. Among authors: srinivasan r. PLoS One. 2018 Nov 2;13(11):e0206223. doi: 10.1371/journal.pone.0206223. eCollection 2018. PLoS One. 2018. PMID: 30388137 Free PMC article.
Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma.
Peng W, Williams LJ, Xu C, Melendez B, McKenzie JA, Chen Y, Jackson HL, Voo KS, Mbofung RM, Leahey SE, Wang J, Lizee G, Tawbi HA, Davies MA, Hoos A, Smothers J, Srinivasan R, Paul EM, Yanamandra N, Hwu P. Peng W, et al. Among authors: srinivasan r. Clin Cancer Res. 2019 Nov 1;25(21):6406-6416. doi: 10.1158/1078-0432.CCR-19-1259. Epub 2019 Aug 1. Clin Cancer Res. 2019. PMID: 31371342 Free PMC article.
T Cell- and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer.
Washburn ML, Wang Z, Walton AH, Goedegebuure SP, Figueroa DJ, Van Horn S, Grossman J, Remlinger K, Madsen H, Brown J, Srinivasan R, Wolf AI, Berger SB, Yi VN, Hawkins WG, Fields RC, Hotchkiss RS. Washburn ML, et al. Among authors: srinivasan r. J Immunol. 2019 Oct 1;203(7):1897-1908. doi: 10.4049/jimmunol.1900560. Epub 2019 Sep 4. J Immunol. 2019. PMID: 31484735 Free PMC article. Clinical Trial.
Deep-learning enabled ultrasound based detection of gallbladder cancer in northern India: a prospective diagnostic study.
Gupta P, Basu S, Rana P, Dutta U, Soundararajan R, Kalage D, Chhabra M, Singh S, Yadav TD, Gupta V, Kaman L, Das CK, Gupta P, Saikia UN, Srinivasan R, Sandhu MS, Arora C. Gupta P, et al. Among authors: srinivasan r. Lancet Reg Health Southeast Asia. 2023 Sep 11;24:100279. doi: 10.1016/j.lansea.2023.100279. eCollection 2024 May. Lancet Reg Health Southeast Asia. 2023. PMID: 38756152 Free PMC article.
Methodology for adapting a co-created early childhood development intervention and implementation strategies for use by frontline workers in India and Guatemala: a systematic application of the FRAME-IS framework.
Bandal A, Hernández S, Mustafa R, Choy K, Edwards N, Guarchaj M, Mejía Alvarez M, Sane A, Tschida S, Maliye C, Miller A, Raut A, Srinivasan R, Turner M, Wagenaar BH, Ertem I, Grazioso MDP, Gupta SS, Krishnamurthy V, Rohloff P. Bandal A, et al. Among authors: srinivasan r. Glob Health Action. 2024 Dec 31;17(1):2338324. doi: 10.1080/16549716.2024.2338324. Epub 2024 May 10. Glob Health Action. 2024. PMID: 38726569 Free PMC article.
1,785 results