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Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore.
Cozzi M, Failla M, Gianquinto E, Kovachka S, Buoli Comani V, Compari C, De Bei O, Giaccari R, Marchesani F, Marchetti M, Ronda L, Rolando B, Baroni M, Cruciani G, Campanini B, Bettati S, Faggiano S, Lazzarato L, Spyrakis F. Cozzi M, et al. Among authors: spyrakis f. Sci Rep. 2024 Apr 9;14(1):8272. doi: 10.1038/s41598-024-55931-8. Sci Rep. 2024. PMID: 38594253 Free PMC article.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
De Bei O, Marchetti M, Ronda L, Gianquinto E, Lazzarato L, Chirgadze DY, Hardwick SW, Cooper LR, Spyrakis F, Luisi BF, Campanini B, Bettati S. De Bei O, et al. Among authors: spyrakis f. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2116708119. doi: 10.1073/pnas.2116708119. Epub 2022 Mar 31. Proc Natl Acad Sci U S A. 2022. PMID: 35357971 Free PMC article.
Rational Design of a User-Friendly Aptamer/Peptide-Based Device for the Detection of Staphylococcus aureus.
Ronda L, Tonelli A, Sogne E, Autiero I, Spyrakis F, Pellegrino S, Abbiati G, Maffioli E, Schulte C, Piano R, Cozzini P, Mozzarelli A, Bettati S, Clerici F, Milani P, Lenardi C, Tedeschi G, Gelmi ML. Ronda L, et al. Among authors: spyrakis f. Sensors (Basel). 2020 Sep 2;20(17):4977. doi: 10.3390/s20174977. Sensors (Basel). 2020. PMID: 32887407 Free PMC article.
Expanding the chemical space of human serine racemase inhibitors.
Dellafiora L, Marchetti M, Spyrakis F, Orlandi V, Campanini B, Cruciani G, Cozzini P, Mozzarelli A. Dellafiora L, et al. Among authors: spyrakis f. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4297-303. doi: 10.1016/j.bmcl.2015.07.081. Epub 2015 Aug 4. Bioorg Med Chem Lett. 2015. PMID: 26283510
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria.
Bersani M, Failla M, Vascon F, Gianquinto E, Bertarini L, Baroni M, Cruciani G, Verdirosa F, Sannio F, Docquier JD, Cendron L, Spyrakis F, Lazzarato L, Tondi D. Bersani M, et al. Among authors: spyrakis f. Pharmaceuticals (Basel). 2023 Dec 2;16(12):1682. doi: 10.3390/ph16121682. Pharmaceuticals (Basel). 2023. PMID: 38139809 Free PMC article.
114 results