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Tricuspid regurgitant jet velocity and myocardial tissue Doppler parameters predict mortality in a cohort of patients with sickle cell disease spanning from pediatric to adult age groups - revisiting this controversial concept after 16 years of additional evidence.
Shah P, Suriany S, Kato R, Bush AM, Chalacheva P, Veluswamy S, Denton CC, Russell K, Khaleel M, Forman HJ, Khoo MCK, Sposto R, Coates TD, Wood JC, Detterich J. Shah P, et al. Among authors: sposto r. Am J Hematol. 2021 Jan;96(1):31-39. doi: 10.1002/ajh.26003. Epub 2020 Oct 12. Am J Hematol. 2021. PMID: 32944977 Free PMC article. Clinical Trial.
Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain.
Khaleel M, Puliyel M, Shah P, Sunwoo J, Kato RM, Chalacheva P, Thuptimdang W, Detterich J, Wood JC, Tsao J, Zeltzer L, Sposto R, Khoo MCK, Coates TD. Khaleel M, et al. Among authors: sposto r. Am J Hematol. 2017 Nov;92(11):1137-1145. doi: 10.1002/ajh.24858. Epub 2017 Aug 17. Am J Hematol. 2017. PMID: 28707371 Free PMC article.
Individual red blood cell nitric oxide production in sickle cell anemia: Nitric oxide production is increased and sickle shaped cells have unique morphologic change compared to discoid cells.
Suriany S, Xu I, Liu H, Ulker P, Fernandez GE, Sposto R, Borzage M, Wenby R, Meiselman HJ, Forman HJ, Coates TD, Detterich JA. Suriany S, et al. Among authors: sposto r. Free Radic Biol Med. 2021 Aug 1;171:143-155. doi: 10.1016/j.freeradbiomed.2021.05.007. Epub 2021 May 8. Free Radic Biol Med. 2021. PMID: 33974976
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.
Pommert L, Schafer ES, Malvar J, Gossai N, Florendo E, Pulakanti K, Heimbruch K, Stelloh C, Chi YY, Sposto R, Rao S, Huynh VT, Brown P, Chang BH, Colace SI, Hermiston ML, Heym K, Hutchinson RJ, Kaplan JA, Mody R, O'Brien TA, Place AE, Shaw PH, Ziegler DS, Wayne A, Bhojwani D, Burke MJ. Pommert L, et al. Among authors: sposto r. Am J Hematol. 2022 May;97(5):613-622. doi: 10.1002/ajh.26510. Epub 2022 Mar 8. Am J Hematol. 2022. PMID: 35180323 Free PMC article. Clinical Trial.
233 results