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Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E.
J Struct Biol. 2022 Sep;214(3):107876. doi: 10.1016/j.jsb.2022.107876. Epub 2022 Jun 20.
J Struct Biol. 2022.
PMID: 35738335
Free article.
Solution structure of deglycosylated human IgG1 shows the role of CH2 glycans in its conformation.
Spiteri VA, Doutch J, Rambo RP, Gor J, Dalby PA, Perkins SJ.
Spiteri VA, et al.
Biophys J. 2021 May 4;120(9):1814-1834. doi: 10.1016/j.bpj.2021.02.038. Epub 2021 Mar 4.
Biophys J. 2021.
PMID: 33675758
Free PMC article.
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Solution structures of human myeloma IgG3 antibody reveal extended Fab and Fc regions relative to the other IgG subclasses.
Spiteri VA, Goodall M, Doutch J, Rambo RP, Gor J, Perkins SJ.
Spiteri VA, et al.
J Biol Chem. 2021 Sep;297(3):100995. doi: 10.1016/j.jbc.2021.100995. Epub 2021 Jul 22.
J Biol Chem. 2021.
PMID: 34302810
Free PMC article.
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Using atomistic solution scattering modelling to elucidate the role of the Fc glycans in human IgG4.
Spiteri VA, Doutch J, Rambo RP, Bhatt JS, Gor J, Dalby PA, Perkins SJ.
Spiteri VA, et al.
PLoS One. 2024 Apr 1;19(4):e0300964. doi: 10.1371/journal.pone.0300964. eCollection 2024.
PLoS One. 2024.
PMID: 38557973
Free PMC article.
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Breaking free from the crystal lattice: Structural biology in solution to study protein degraders.
Haubrich K, Spiteri VA, Farnaby W, Sobott F, Ciulli A.
Haubrich K, et al. Among authors: spiteri va.
Curr Opin Struct Biol. 2023 Apr;79:102534. doi: 10.1016/j.sbi.2023.102534. Epub 2023 Feb 15.
Curr Opin Struct Biol. 2023.
PMID: 36804675
Free article.
Review.
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Antibodies to FXa and thrombin in patients with SLE differentially regulate C3 and C5 cleavage.
McDonnell T, Amarnani R, Spicer C, Jbari H, Pericleous C, Spiteri VA, Wincup C, Artim-Esen B, Mackie I, Botto M, Rahman A, Giles I.
McDonnell T, et al. Among authors: spiteri va.
Lupus Sci Med. 2022 Aug;9(1):e000738. doi: 10.1136/lupus-2022-000738.
Lupus Sci Med. 2022.
PMID: 36007979
Free PMC article.
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