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Microglia regulate central nervous system myelin growth and integrity.
McNamara NB, Munro DAD, Bestard-Cuche N, Uyeda A, Bogie JFJ, Hoffmann A, Holloway RK, Molina-Gonzalez I, Askew KE, Mitchell S, Mungall W, Dodds M, Dittmayer C, Moss J, Rose J, Szymkowiak S, Amann L, McColl BW, Prinz M, Spires-Jones TL, Stenzel W, Horsburgh K, Hendriks JJA, Pridans C, Muramatsu R, Williams A, Priller J, Miron VE. McNamara NB, et al. Nature. 2023 Jan;613(7942):120-129. doi: 10.1038/s41586-022-05534-y. Epub 2022 Dec 14. Nature. 2023. PMID: 36517604 Free PMC article.
Reflections on the past two decades of neuroscience.
Bassett DS, Cullen KE, Eickhoff SB, Farah MJ, Goda Y, Haggard P, Hu H, Hurd YL, Josselyn SA, Khakh BS, Knoblich JA, Poirazi P, Poldrack RA, Prinz M, Roelfsema PR, Spires-Jones TL, Sur M, Ueda HR. Bassett DS, et al. Nat Rev Neurosci. 2020 Oct;21(10):524-534. doi: 10.1038/s41583-020-0363-6. Epub 2020 Sep 2. Nat Rev Neurosci. 2020. PMID: 32879507 Review.
Selective vulnerability of inhibitory networks in multiple sclerosis.
Zoupi L, Booker SA, Eigel D, Werner C, Kind PC, Spires-Jones TL, Newland B, Williams AC. Zoupi L, et al. Acta Neuropathol. 2021 Mar;141(3):415-429. doi: 10.1007/s00401-020-02258-z. Epub 2021 Jan 15. Acta Neuropathol. 2021. PMID: 33449171 Free PMC article.
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, Hooley M, Hampton D, Torvell M, Johnson DA, McQueen J, Baxter P, Sabari-Sankar K, Qiu J, He X, Fowler J, Febery J, Gregory J, Rose J, Tulloch J, Loan J, Story D, McDade K, Smith AM, Greer P, Ball M, Kind PC, Matthews PM, Smith C, Dando O, Spires-Jones TL, Johnson JA, Chandran S, Hardingham GE. Jiwaji Z, et al. Nat Commun. 2022 Jan 10;13(1):135. doi: 10.1038/s41467-021-27702-w. Nat Commun. 2022. PMID: 35013236 Free PMC article.
A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens.
Stevenson AJ, McCartney DL, Gadd DA, Shireby G, Hillary RF, King D, Tzioras M, Wrobel N, McCafferty S, Murphy L, McColl BW, Redmond P, Taylor AM, Harris SE, Russ TC, McIntosh AM, Mill J, Smith C, Deary IJ, Cox SR, Marioni RE, Spires-Jones TL. Stevenson AJ, et al. Eur J Neurosci. 2022 Nov;56(9):5637-5649. doi: 10.1111/ejn.15661. Epub 2022 Apr 6. Eur J Neurosci. 2022. PMID: 35362642 Free PMC article.
Tau association with synaptic vesicles causes presynaptic dysfunction.
Zhou L, McInnes J, Wierda K, Holt M, Herrmann AG, Jackson RJ, Wang YC, Swerts J, Beyens J, Miskiewicz K, Vilain S, Dewachter I, Moechars D, De Strooper B, Spires-Jones TL, De Wit J, Verstreken P. Zhou L, et al. Nat Commun. 2017 May 11;8:15295. doi: 10.1038/ncomms15295. Nat Commun. 2017. PMID: 28492240 Free PMC article.
154 results