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Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.
Saulle E, Spinello I, Quaranta MT, Pasquini L, Pelosi E, Iorio E, Castelli G, Chirico M, Pisanu ME, Ottone T, Voso MT, Testa U, Labbaye C. Saulle E, et al. Among authors: spinello i. Front Oncol. 2021 Feb 5;10:621458. doi: 10.3389/fonc.2020.621458. eCollection 2020. Front Oncol. 2021. PMID: 33614502 Free PMC article.
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.
Spinello I, Saulle E, Quaranta MT, Pasquini L, Pelosi E, Castelli G, Ottone T, Voso MT, Testa U, Labbaye C. Spinello I, et al. Haematologica. 2019 May;104(5):973-985. doi: 10.3324/haematol.2018.199661. Epub 2018 Nov 22. Haematologica. 2019. PMID: 30467201 Free PMC article.
Brain Death Determination.
Spinello IM. Spinello IM. J Intensive Care Med. 2015 Sep;30(6):326-37. doi: 10.1177/0885066613511053. Epub 2013 Nov 12. J Intensive Care Med. 2015. PMID: 24227449 Review.
28 results