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Assessment of the performance of the Ames MPF™ assay: A multicenter collaborative study with six coded chemicals.
Spiliotopoulos D, Koelbert C, Audebert M, Barisch I, Bellet D, Constans M, Czich A, Finot F, Gervais V, Khoury L, Kirchnawy C, Kitamoto S, Le Tesson A, Malesic L, Matsuyama R, Mayrhofer E, Mouche I, Preikschat B, Prielinger L, Rainer B, Roblin C, Wäse K. Spiliotopoulos D, et al. Mutat Res Genet Toxicol Environ Mutagen. 2024 Jan;893:503718. doi: 10.1016/j.mrgentox.2023.503718. Epub 2023 Nov 23. Mutat Res Genet Toxicol Environ Mutagen. 2024. PMID: 38272629
Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing.
Dalle Vedove A, Cazzanelli G, Batiste L, Marchand JR, Spiliotopoulos D, Corsi J, D'Agostino VG, Caflisch A, Lolli G. Dalle Vedove A, et al. Among authors: spiliotopoulos d. ACS Med Chem Lett. 2022 Aug 3;13(9):1434-1443. doi: 10.1021/acsmedchemlett.2c00173. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105334 Free PMC article.
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors.
Unzue A, Jessen-Trefzer C, Spiliotopoulos D, Gaudio E, Tarantelli C, Dong J, Zhao H, Pachmayr J, Zahler S, Bernasconi E, Sartori G, Cascione L, Bertoni F, Śledź P, Caflisch A, Nevado C. Unzue A, et al. Among authors: spiliotopoulos d. RSC Med Chem. 2020 May 19;11(6):665-675. doi: 10.1039/d0md00049c. eCollection 2020 Jun 1. RSC Med Chem. 2020. PMID: 33479666 Free PMC article.
Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
Dolbois A, Batiste L, Wiedmer L, Dong J, Brütsch M, Huang D, Deerain NM, Spiliotopoulos D, Cheng-Sánchez I, Laul E, Nevado C, Śledź P, Caflisch A. Dolbois A, et al. Among authors: spiliotopoulos d. ACS Med Chem Lett. 2020 Jun 30;11(8):1573-1580. doi: 10.1021/acsmedchemlett.0c00080. eCollection 2020 Aug 13. ACS Med Chem Lett. 2020. PMID: 32832026 Free PMC article.
Ligand retargeting by binding site analogy.
Wiedmer L, Schärer C, Spiliotopoulos D, Hürzeler M, Śledź P, Caflisch A. Wiedmer L, et al. Among authors: spiliotopoulos d. Eur J Med Chem. 2019 Aug 1;175:107-113. doi: 10.1016/j.ejmech.2019.04.037. Epub 2019 Apr 25. Eur J Med Chem. 2019. PMID: 31077996
Social media analysis during political turbulence.
Antonakaki D, Spiliotopoulos D, V Samaras C, Pratikakis P, Ioannidis S, Fragopoulou P. Antonakaki D, et al. Among authors: spiliotopoulos d. PLoS One. 2017 Oct 31;12(10):e0186836. doi: 10.1371/journal.pone.0186836. eCollection 2017. PLoS One. 2017. PMID: 29088263 Free PMC article.
Discovery of BAZ2A bromodomain ligands.
Spiliotopoulos D, Wamhoff EC, Lolli G, Rademacher C, Caflisch A. Spiliotopoulos D, et al. Eur J Med Chem. 2017 Oct 20;139:564-572. doi: 10.1016/j.ejmech.2017.08.028. Epub 2017 Aug 12. Eur J Med Chem. 2017. PMID: 28837921
23 results