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Efficacy and Safety of Lenabasum, a Cannabinoid Type 2 Receptor Agonist, in a Phase 3 Randomized Trial in Diffuse Cutaneous Systemic Sclerosis.
Spiera R, Kuwana M, Khanna D, Hummers L, Frech TM, Stevens W, Matucci-Cerinic M, Kafaja S, Distler O, Jun JB, Levy Y, Leszcyzński P, Gordon J, Steen V, Lee EB, Jankowski T, Litinsky I, Chung L, Hsu V, Mayes M, Sandorfi N, Simms RW, Finzel S, de Vries-Bouwstra J, Constantine S, Dgetluck N, Dinh Q, Bloom BJ, Furst DE, White B, Denton CP; RESOLVE-1 Study Group. Spiera R, et al. Arthritis Rheumatol. 2023 Sep;75(9):1608-1618. doi: 10.1002/art.42510. Epub 2023 Jun 15. Arthritis Rheumatol. 2023. PMID: 37098795 Free article. Clinical Trial.
A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen treatment in patients with diffuse cutaneous systemic sclerosis: I. oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease.
Postlethwaite AE, Wong WK, Clements P, Chatterjee S, Fessler BJ, Kang AH, Korn J, Mayes M, Merkel PA, Molitor JA, Moreland L, Rothfield N, Simms RW, Smith EA, Spiera R, Steen V, Warrington K, White B, Wigley F, Furst DE. Postlethwaite AE, et al. Among authors: spiera r. Arthritis Rheum. 2008 Jun;58(6):1810-22. doi: 10.1002/art.23501. Arthritis Rheum. 2008. PMID: 18512816 Free PMC article. Clinical Trial.
Stimulation with type I collagen induces changes in gene expression in peripheral blood mononuclear cells from patients with diffuse cutaneous systemic sclerosis (scleroderma).
Atamas SP, Luzina IG, Ingels J, Choi J, Wong WK, Furst DE, Clements PJ; Investigators of the Oral Collagen Trial in Scleroderma; Postlethwaite AE. Atamas SP, et al. Clin Exp Immunol. 2010 Sep;161(3):426-35. doi: 10.1111/j.1365-2249.2010.04189.x. Clin Exp Immunol. 2010. PMID: 20529088 Free PMC article.
A longitudinal biomarker for the extent of skin disease in patients with diffuse cutaneous systemic sclerosis.
Rice LM, Ziemek J, Stratton EA, McLaughlin SR, Padilla CM, Mathes AL, Christmann RB, Stifano G, Browning JL, Whitfield ML, Spiera RF, Gordon JK, Simms RW, Zhang Y, Lafyatis R. Rice LM, et al. Among authors: spiera rf. Arthritis Rheumatol. 2015 Nov;67(11):3004-15. doi: 10.1002/art.39287. Arthritis Rheumatol. 2015. PMID: 26240058 Free PMC article.
198 results