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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions.
Esnault C, Magat T, Zine El Aabidine A, Garcia-Oliver E, Cucchiarini A, Bouchouika S, Lleres D, Goerke L, Luo Y, Verga D, Lacroix L, Feil R, Spicuglia S, Mergny JL, Andrau JC. Esnault C, et al. Among authors: spicuglia s. Nat Genet. 2023 Aug;55(8):1359-1369. doi: 10.1038/s41588-023-01437-4. Epub 2023 Jul 3. Nat Genet. 2023. PMID: 37400615 Free article.
CD8+ T Cells from Human Neonates Are Biased toward an Innate Immune Response.
Galindo-Albarrán AO, López-Portales OH, Gutiérrez-Reyna DY, Rodríguez-Jorge O, Sánchez-Villanueva JA, Ramírez-Pliego O, Bergon A, Loriod B, Holota H, Imbert J, Hernández-Mendoza A, Ferrier P, Carrillo-de Santa Pau E, Valencia A, Spicuglia S, Santana MA. Galindo-Albarrán AO, et al. Among authors: spicuglia s. Cell Rep. 2016 Nov 15;17(8):2151-2160. doi: 10.1016/j.celrep.2016.10.056. Cell Rep. 2016. PMID: 27851975 Free article.
Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.
Le Noir S, Ben Abdelali R, Lelorch M, Bergeron J, Sungalee S, Payet-Bornet D, Villarèse P, Petit A, Callens C, Lhermitte L, Baranger L, Radford-Weiss I, Grégoire MJ, Dombret H, Ifrah N, Spicuglia S, Romana S, Soulier J, Nadel B, Macintyre E, Asnafi V. Le Noir S, et al. Among authors: spicuglia s. Blood. 2012 Oct 18;120(16):3298-309. doi: 10.1182/blood-2012-04-425488. Epub 2012 Sep 4. Blood. 2012. PMID: 22948044 Free article.
[Functions of lncRNA in development and diseases].
Mathieu EL, Belhocine M, Dao LT, Puthier D, Spicuglia S. Mathieu EL, et al. Among authors: spicuglia s. Med Sci (Paris). 2014 Aug-Sep;30(8-9):790-6. doi: 10.1051/medsci/20143008018. Epub 2014 Sep 1. Med Sci (Paris). 2014. PMID: 25174757 Free article. Review. French.
TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.
Dadi S, Le Noir S, Payet-Bornet D, Lhermitte L, Zacarias-Cabeza J, Bergeron J, Villarèse P, Vachez E, Dik WA, Millien C, Radford I, Verhoeyen E, Cosset FL, Petit A, Ifrah N, Dombret H, Hermine O, Spicuglia S, Langerak AW, Macintyre EA, Nadel B, Ferrier P, Asnafi V. Dadi S, et al. Among authors: spicuglia s. Cancer Cell. 2012 Apr 17;21(4):563-76. doi: 10.1016/j.ccr.2012.02.013. Cancer Cell. 2012. PMID: 22516263 Free article.
Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.
Bond J, Graux C, Lhermitte L, Lara D, Cluzeau T, Leguay T, Cieslak A, Trinquand A, Pastoret C, Belhocine M, Spicuglia S, Lheritier V, Leprêtre S, Thomas X, Huguet F, Ifrah N, Dombret H, Macintyre E, Boissel N, Asnafi V. Bond J, et al. Among authors: spicuglia s. J Clin Oncol. 2017 Aug 10;35(23):2683-2691. doi: 10.1200/JCO.2016.71.8585. Epub 2017 Jun 12. J Clin Oncol. 2017. PMID: 28605290 Clinical Trial.
TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.
Villarese P, Lours C, Trinquand A, Le Noir S, Belhocine M, Lhermitte L, Cieslak A, Tesio M, Petit A, LeLorch M, Spicuglia S, Ifrah N, Dombret H, Langerak AW, Boissel N, Macintyre E, Asnafi V. Villarese P, et al. Among authors: spicuglia s. Leukemia. 2018 Jan;32(1):61-71. doi: 10.1038/leu.2017.176. Epub 2017 Jun 8. Leukemia. 2018. PMID: 28592888 Clinical Trial.
PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax.
Pinton A, Courtois L, Doublet C, Cabannes-Hamy A, Andrieu G, Smith C, Balducci E, Cieslak A, Touzart A, Simonin M, Lhéritier V, Huguet F, Balsat M, Dombret H, Rousselot P, Spicuglia S, Macintyre E, Boissel N, Asnafi V. Pinton A, et al. Among authors: spicuglia s. Clin Cancer Res. 2024 Jan 5;30(1):94-105. doi: 10.1158/1078-0432.CCR-23-2159. Clin Cancer Res. 2024. PMID: 37889114
An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.
Bond J, Marchand T, Touzart A, Cieslak A, Trinquand A, Sutton L, Radford-Weiss I, Lhermitte L, Spicuglia S, Dombret H, Macintyre E, Ifrah N, Hamel JF, Asnafi V. Bond J, et al. Among authors: spicuglia s. Haematologica. 2016 Jun;101(6):732-40. doi: 10.3324/haematol.2015.141218. Epub 2016 Mar 4. Haematologica. 2016. PMID: 26944475 Free PMC article. Clinical Trial.
90 results