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PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax.
Pinton A, Courtois L, Doublet C, Cabannes-Hamy A, Andrieu G, Smith C, Balducci E, Cieslak A, Touzart A, Simonin M, Lhéritier V, Huguet F, Balsat M, Dombret H, Rousselot P, Spicuglia S, Macintyre E, Boissel N, Asnafi V. Pinton A, et al. Among authors: spicuglia s. Clin Cancer Res. 2024 Jan 5;30(1):94-105. doi: 10.1158/1078-0432.CCR-23-2159. Clin Cancer Res. 2024. PMID: 37889114
IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
Courtois L, Cabannes-Hamy A, Kim R, Delecourt M, Pinton A, Charbonnier G, Feroul M, Smith C, Tueur G, Pivert C, Balducci E, Simonin M, Angel LH, Spicuglia S, Boissel N, Andrieu GP, Asnafi V, Rousselot P, Lhermitte L. Courtois L, et al. Among authors: spicuglia s. Blood. 2023 Jul 13;142(2):158-171. doi: 10.1182/blood.2022017948. Blood. 2023. PMID: 37023368
H3K4 tri-methylation provides an epigenetic signature of active enhancers.
Pekowska A, Benoukraf T, Zacarias-Cabeza J, Belhocine M, Koch F, Holota H, Imbert J, Andrau JC, Ferrier P, Spicuglia S. Pekowska A, et al. Among authors: spicuglia s. EMBO J. 2011 Aug 16;30(20):4198-210. doi: 10.1038/emboj.2011.295. EMBO J. 2011. PMID: 21847099 Free PMC article.
Divergent transcription is associated with promoters of transcriptional regulators.
Lepoivre C, Belhocine M, Bergon A, Griffon A, Yammine M, Vanhille L, Zacarias-Cabeza J, Garibal MA, Koch F, Maqbool MA, Fenouil R, Loriod B, Holota H, Gut M, Gut I, Imbert J, Andrau JC, Puthier D, Spicuglia S. Lepoivre C, et al. Among authors: spicuglia s. BMC Genomics. 2013 Dec 23;14:914. doi: 10.1186/1471-2164-14-914. BMC Genomics. 2013. PMID: 24365181 Free PMC article.
[Functions of lncRNA in development and diseases].
Mathieu EL, Belhocine M, Dao LT, Puthier D, Spicuglia S. Mathieu EL, et al. Among authors: spicuglia s. Med Sci (Paris). 2014 Aug-Sep;30(8-9):790-6. doi: 10.1051/medsci/20143008018. Epub 2014 Sep 1. Med Sci (Paris). 2014. PMID: 25174757 Free article. Review. French.
Transcription-dependent generation of a specialized chromatin structure at the TCRβ locus.
Zacarías-Cabeza J, Belhocine M, Vanhille L, Cauchy P, Koch F, Pekowska A, Fenouil R, Bergon A, Gut M, Gut I, Eick D, Imbert J, Ferrier P, Andrau JC, Spicuglia S. Zacarías-Cabeza J, et al. Among authors: spicuglia s. J Immunol. 2015 Apr 1;194(7):3432-43. doi: 10.4049/jimmunol.1400789. Epub 2015 Mar 2. J Immunol. 2015. PMID: 25732733
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