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Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
Sum E, Rapp M, Fröbel P, Le Clech M, Dürr H, Giusti AM, Perro M, Speziale D, Kunz L, Menietti E, Brünker P, Hopfer U, Lechmann M, Sobieniecki A, Appelt B, Adelfio R, Nicolini V, Freimoser-Grundschober A, Jordaan W, Labiano S, Weber F, Emrich T, Christen F, Essig B, Romero P, Trumpfheller C, Umaña P. Sum E, et al. Among authors: speziale d. Clin Cancer Res. 2021 Jul 15;27(14):4036-4053. doi: 10.1158/1078-0432.CCR-20-4001. Epub 2021 Mar 26. Clin Cancer Res. 2021. PMID: 33771854
The Type II Anti-CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus Model.
Marinov AD, Wang H, Bastacky SI, van Puijenbroek E, Schindler T, Speziale D, Perro M, Klein C, Nickerson KM, Shlomchik MJ. Marinov AD, et al. Among authors: speziale d. Arthritis Rheumatol. 2021 May;73(5):826-836. doi: 10.1002/art.41608. Epub 2021 Mar 24. Arthritis Rheumatol. 2021. PMID: 33277983 Free PMC article.
Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model.
Cremasco F, Menietti E, Speziale D, Sam J, Sammicheli S, Richard M, Varol A, Klein C, Umana P, Bacac M, Colombetti S, Perro M. Cremasco F, et al. Among authors: speziale d. PLoS One. 2021 Jan 6;16(1):e0241091. doi: 10.1371/journal.pone.0241091. eCollection 2021. PLoS One. 2021. PMID: 33406104 Free PMC article.
CD19-CD28: An affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.
Sam J, Hofer T, Kuettel C, Claus C, Thom J, Herter S, Georges G, Korfi K, Lechmann M, Eigenmann MJ, Marbach D, Jamois C, Lechner K, Krishnan SM, Gaillard BC, Marinho J, Kronenberg S, Kunz L, Wilson S, Briner S, Gebhardt S, Varol A, Appelt B, Nicolini VG, Speziale D, Bez M, Bommer E, Eckmann J, Hage C, Limani F, Jenni S, Schoenle A, Le Clech M, Vallier JB, Colombetti S, Bacac M, Gasser S, Klein C, Umaña P. Sam J, et al. Among authors: speziale d. Blood. 2024 Mar 4:blood.2023023381. doi: 10.1182/blood.2023023381. Online ahead of print. Blood. 2024. PMID: 38437725 Free article.
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.
Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson KA, Germann P, Unal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D, Zeller R. Lopez-Rios J, et al. Among authors: speziale d. Nature. 2014 Jul 3;511(7507):46-51. doi: 10.1038/nature13289. Epub 2014 Jun 18. Nature. 2014. PMID: 24990743
Seroprevalence of anti-SARS-CoV-2 IgG antibodies in children with household exposure to adults with COVID-19: Preliminary findings.
Buonsenso D, Valentini P, De Rose C, Pata D, Sinatti D, Speziale D, Ricci R, Carfì A, Landi F, Ferrari V, De Maio F, Palucci I, Sanguinetti M, Sali M; Gemelli Against COVID-19 Post-Acute Care Study Group. Buonsenso D, et al. Among authors: speziale d. Pediatr Pulmonol. 2021 Jun;56(6):1374-1377. doi: 10.1002/ppul.25280. Epub 2021 Feb 1. Pediatr Pulmonol. 2021. PMID: 33470561 Free PMC article.
21 results