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Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury.
Akhmedov A, Bonetti NR, Reiner MF, Spescha RD, Amstalden H, Merlini M, Gaul DS, Diaz-Cañestro C, Briand-Schumacher S, Spescha RS, Semerano A, Giacalone G, Savarese G, Montecucco F, Kulic L, Nitsch RM, Matter CM, Kullak-Ublick GA, Sessa M, Lüscher TF, Beer JH, Liberale L, Camici GG. Akhmedov A, et al. Among authors: spescha rd. J Cereb Blood Flow Metab. 2019 Nov;39(11):2233-2245. doi: 10.1177/0271678X18793266. Epub 2018 Aug 3. J Cereb Blood Flow Metab. 2019. PMID: 30073881 Free PMC article.
Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke.
Spescha RD, Klohs J, Semerano A, Giacalone G, Derungs RS, Reiner MF, Rodriguez Gutierrez D, Mendez-Carmona N, Glanzmann M, Savarese G, Kränkel N, Akhmedov A, Keller S, Mocharla P, Kaufmann MR, Wenger RH, Vogel J, Kulic L, Nitsch RM, Beer JH, Peruzzotti-Jametti L, Sessa M, Lüscher TF, Camici GG. Spescha RD, et al. Eur Heart J. 2015 Jul 1;36(25):1590-600. doi: 10.1093/eurheartj/ehv140. Epub 2015 Apr 22. Eur Heart J. 2015. PMID: 25904764 Free article.
Reduced nitric oxide bioavailability mediates cerebroarterial dysfunction independent of cerebral amyloid angiopathy in a mouse model of Alzheimer's disease.
Merlini M, Shi Y, Keller S, Savarese G, Akhmedov A, Derungs R, Spescha RD, Kulic L, Nitsch RM, Lüscher TF, Camici GG. Merlini M, et al. Among authors: spescha rd. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H232-H238. doi: 10.1152/ajpheart.00607.2016. Epub 2016 Nov 11. Am J Physiol Heart Circ Physiol. 2017. PMID: 27836896 Free article.
Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways.
Akhmedov A, Camici GG, Reiner MF, Bonetti NR, Costantino S, Holy EW, Spescha RD, Stivala S, Schaub Clerigué A, Speer T, Breitenstein A, Manz J, Lohmann C, Paneni F, Beer JH, Lüscher TF. Akhmedov A, et al. Among authors: spescha rd. Cardiovasc Res. 2017 Apr 1;113(5):498-507. doi: 10.1093/cvr/cvx015. Cardiovasc Res. 2017. PMID: 28199510
Expression of the aging gene p66Shc is increased in peripheral blood monocytes of patients with acute coronary syndrome but not with stable coronary artery disease.
Franzeck FC, Hof D, Spescha RD, Hasun M, Akhmedov A, Steffel J, Shi Y, Cosentino F, Tanner FC, von Eckardstein A, Maier W, Lüscher TF, Wyss CA, Camici GG. Franzeck FC, et al. Among authors: spescha rd. Atherosclerosis. 2012 Jan;220(1):282-6. doi: 10.1016/j.atherosclerosis.2011.10.035. Epub 2011 Nov 2. Atherosclerosis. 2012. PMID: 22100252 Free article.
Angiopoietin-like 4 and ischaemic stroke: a promising start.
Spescha RD, Sessa M, Camici GG. Spescha RD, et al. Eur Heart J. 2013 Dec;34(47):3603-5. doi: 10.1093/eurheartj/eht183. Epub 2013 May 31. Eur Heart J. 2013. PMID: 23729690 Free article. No abstract available.
The MAP kinase JNK2 mediates cigarette smoke-induced arterial thrombosis.
Breitenstein A, Stämpfli SF, Reiner MF, Shi Y, Keller S, Akhmedov A, Schaub Clerigué A, Spescha RD, Beer HJ, Lüscher TF, Tanner FC, Camici GG. Breitenstein A, et al. Among authors: spescha rd. Thromb Haemost. 2017 Jan 5;117(1):83-89. doi: 10.1160/TH16-05-0351. Epub 2016 Oct 20. Thromb Haemost. 2017. PMID: 27761579
13 results