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Modeling human adaptive immune responses with tonsil organoids.
Wagar LE, Salahudeen A, Constantz CM, Wendel BS, Lyons MM, Mallajosyula V, Jatt LP, Adamska JZ, Blum LK, Gupta N, Jackson KJL, Yang F, Röltgen K, Roskin KM, Blaine KM, Meister KD, Ahmad IN, Cortese M, Dora EG, Tucker SN, Sperling AI, Jain A, Davies DH, Felgner PL, Hammer GB, Kim PS, Robinson WH, Boyd SD, Kuo CJ, Davis MM. Wagar LE, et al. Among authors: sperling ai. Nat Med. 2021 Jan;27(1):125-135. doi: 10.1038/s41591-020-01145-0. Epub 2021 Jan 11. Nat Med. 2021. PMID: 33432170 Free PMC article.
Signaling through CD43 regulates CD4 T-cell trafficking.
Mody PD, Cannon JL, Bandukwala HS, Blaine KM, Schilling AB, Swier K, Sperling AI. Mody PD, et al. Among authors: sperling ai. Blood. 2007 Oct 15;110(8):2974-82. doi: 10.1182/blood-2007-01-065276. Epub 2007 Jul 16. Blood. 2007. PMID: 17638845 Free PMC article.
Fas ligand expression on T cells is sufficient to prevent prolonged airway inflammation in a murine model of asthma.
Tong J, Clay BS, Ferreira CM, Bandukwala HS, Moore TV, Blaine KM, Williams JW, Hoffman LM, Hamann KJ, Shilling RA, Weinstock JV, Sperling AI. Tong J, et al. Among authors: sperling ai. Am J Respir Cell Mol Biol. 2010 Sep;43(3):342-8. doi: 10.1165/rcmb.2008-0454OC. Epub 2009 Oct 23. Am J Respir Cell Mol Biol. 2010. PMID: 19855087 Free PMC article.
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses.
Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polić B, Al-Harthi L, Sperling AI, Guevara-Patiño JA. Zloza A, et al. Among authors: sperling ai. Nat Med. 2012 Feb 26;18(3):422-8. doi: 10.1038/nm.2683. Nat Med. 2012. PMID: 22366950 Free PMC article.
Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.
Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Williams JW, et al. Among authors: sperling ai. Nat Commun. 2013;4:2990. doi: 10.1038/ncomms3990. Nat Commun. 2013. PMID: 24356538 Free PMC article.
141 results