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Page 1
Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions.
Montgomery JE, Donnelly JA, Fanning SW, Speltz TE, Shangguan X, Coukos JS, Greene GL, Moellering RE. Montgomery JE, et al. Among authors: speltz te. J Am Chem Soc. 2019 Oct 16;141(41):16374-16381. doi: 10.1021/jacs.9b07578. Epub 2019 Sep 26. J Am Chem Soc. 2019. PMID: 31523967 Free PMC article.
Protein targeting with SAF(er) electrophiles.
Speltz TE, Moellering RE. Speltz TE, et al. Nat Chem. 2020 Oct;12(10):885-887. doi: 10.1038/s41557-020-00553-6. Nat Chem. 2020. PMID: 32978603 No abstract available.
Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway.
Richardson BG, Jain AD, Speltz TE, Moore TW. Richardson BG, et al. Among authors: speltz te. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2261-8. doi: 10.1016/j.bmcl.2015.04.019. Epub 2015 Apr 16. Bioorg Med Chem Lett. 2015. PMID: 25937010 Free PMC article. Review.
Recent structural advances in constrained helical peptides.
Skowron KJ, Speltz TE, Moore TW. Skowron KJ, et al. Among authors: speltz te. Med Res Rev. 2019 Mar;39(2):749-770. doi: 10.1002/med.21540. Epub 2018 Oct 11. Med Res Rev. 2019. PMID: 30307621 Free PMC article. Review.
Steroid receptor/coactivator binding inhibitors: An update.
Skowron KJ, Booker K, Cheng C, Creed S, David BP, Lazzara PR, Lian A, Siddiqui Z, Speltz TE, Moore TW. Skowron KJ, et al. Among authors: speltz te. Mol Cell Endocrinol. 2019 Aug 1;493:110471. doi: 10.1016/j.mce.2019.110471. Epub 2019 Jun 1. Mol Cell Endocrinol. 2019. PMID: 31163202 Free PMC article. Review.