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The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2).
Velanis CN, Perera P, Thomson B, de Leau E, Liang SC, Hartwig B, Förderer A, Thornton H, Arede P, Chen J, Webb KM, Gümüs S, De Jaeger G, Page CA, Hancock CN, Spanos C, Rappsilber J, Voigt P, Turck F, Wellmer F, Goodrich J. Velanis CN, et al. Among authors: spanos c. PLoS Genet. 2020 May 28;16(5):e1008681. doi: 10.1371/journal.pgen.1008681. eCollection 2020 May. PLoS Genet. 2020. PMID: 32463832 Free PMC article.
Repo-Man/PP1 regulates heterochromatin formation in interphase.
de Castro IJ, Budzak J, Di Giacinto ML, Ligammari L, Gokhan E, Spanos C, Moralli D, Richardson C, de Las Heras JI, Salatino S, Schirmer EC, Ullman KS, Bickmore WA, Green C, Rappsilber J, Lamble S, Goldberg MW, Vinciotti V, Vagnarelli P. de Castro IJ, et al. Among authors: spanos c. Nat Commun. 2017 Jan 16;8:14048. doi: 10.1038/ncomms14048. Nat Commun. 2017. PMID: 28091603 Free PMC article.
Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA, Barbon M, Rappsilber J, Stillman B, Speck C, Li H. Yuan Z, et al. Among authors: spanos c. Nat Struct Mol Biol. 2017 Mar;24(3):316-324. doi: 10.1038/nsmb.3372. Epub 2017 Feb 13. Nat Struct Mol Biol. 2017. PMID: 28191893 Free PMC article.
92 results