Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors.
Spallarossa A, Cesarini S, Ranise A, Ponassi M, Unge T, Bolognesi M.
Spallarossa A, et al.
Biochem Biophys Res Commun. 2008 Jan 25;365(4):764-70. doi: 10.1016/j.bbrc.2007.11.036. Epub 2007 Nov 21.
Biochem Biophys Res Commun. 2008.
PMID: 18035053
O-Phthalimidoethyl-N-arylthiocarbamates (TCs) have been recently identified as a new class of potent HIV-1 reverse transcriptase (RT) non-nucleoside inhibitors (NNRTIs), by means of computer-aided drug design techniques [Ranise A. Spallarossa, S. Cesarini, F. …
O-Phthalimidoethyl-N-arylthiocarbamates (TCs) have been recently identified as a new class of potent HIV-1 reverse transcriptase (RT) …