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PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice.
Canale V, Spalinger MR, Alvarez R, Sayoc-Becerra A, Sanati G, Manz S, Chatterjee P, Santos AN, Lei H, Jahng S, Chu T, Shawki A, Hanson E, Eckmann L, Ouellette AJ, McCole DF. Canale V, et al. Among authors: spalinger mr. Cell Mol Gastroenterol Hepatol. 2023;16(1):39-62. doi: 10.1016/j.jcmgh.2023.03.009. Epub 2023 Apr 7. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37030630 Free PMC article.
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Spalinger MR, Kasper S, Gottier C, Lang S, Atrott K, Vavricka SR, Scharl S, Raselli T, Frey-Wagner I, Gutte PM, Grütter MG, Beer HD, Contassot E, Chan AC, Dai X, Rawlings DJ, Mair F, Becher B, Falk W, Fried M, Rogler G, Scharl M. Spalinger MR, et al. J Clin Invest. 2016 Nov 1;126(11):4388. doi: 10.1172/JCI90897. Epub 2016 Nov 1. J Clin Invest. 2016. PMID: 27801679 Free PMC article. No abstract available.
Loss of PTPN22 abrogates the beneficial effect of cohousing-mediated fecal microbiota transfer in murine colitis.
Spalinger MR, Schwarzfischer M, Hering L, Shawki A, Sayoc A, Santos A, Gottier C, Lang S, Bäbler K, Geirnaert A, Lacroix C, Leventhal GE, Dai X, Rawlings D, Chan AA, Rogler G, McCole DF, Scharl M. Spalinger MR, et al. Mucosal Immunol. 2019 Nov;12(6):1336-1347. doi: 10.1038/s41385-019-0201-1. Epub 2019 Sep 9. Mucosal Immunol. 2019. PMID: 31501515 Free article.
Presence of PTPN2 SNP rs1893217 Enhances the Anti-inflammatory Effect of Spermidine.
Niechcial A, Butter M, Manz S, Obialo N, Bäbler K, van der Lely L, Lang S, Gottier C, McCole DF, Scharl M, Spalinger MR. Niechcial A, et al. Among authors: spalinger mr. Inflamm Bowel Dis. 2020 Jun 18;26(7):1038-1049. doi: 10.1093/ibd/izaa013. Inflamm Bowel Dis. 2020. PMID: 32031616 Free PMC article.
78 results