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"In vitro" 3D models of tumor-immune system interaction.
Hirt C, Papadimitropoulos A, Mele V, Muraro MG, Mengus C, Iezzi G, Terracciano L, Martin I, Spagnoli GC. Hirt C, et al. Among authors: spagnoli gc. Adv Drug Deliv Rev. 2014 Dec 15;79-80:145-54. doi: 10.1016/j.addr.2014.05.003. Epub 2014 May 9. Adv Drug Deliv Rev. 2014. PMID: 24819215 Review.
Maintenance of Primary Human Colorectal Cancer Microenvironment Using a Perfusion Bioreactor-Based 3D Culture System.
Manfredonia C, Muraro MG, Hirt C, Mele V, Governa V, Papadimitropoulos A, Däster S, Soysal SD, Droeser RA, Mechera R, Oertli D, Rosso R, Bolli M, Zettl A, Terracciano LM, Spagnoli GC, Martin I, Iezzi G. Manfredonia C, et al. Among authors: spagnoli gc. Adv Biosyst. 2019 Apr;3(4):e1800300. doi: 10.1002/adbi.201800300. Epub 2019 Mar 7. Adv Biosyst. 2019. PMID: 32627426
New dimensions in tumor immunology: what does 3D culture reveal?
Feder-Mengus C, Ghosh S, Reschner A, Martin I, Spagnoli GC. Feder-Mengus C, et al. Among authors: spagnoli gc. Trends Mol Med. 2008 Aug;14(8):333-40. doi: 10.1016/j.molmed.2008.06.001. Epub 2008 Jul 7. Trends Mol Med. 2008. PMID: 18614399
Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β.
Mele V, Muraro MG, Calabrese D, Pfaff D, Amatruda N, Amicarella F, Kvinlaug B, Bocelli-Tyndall C, Martin I, Resink TJ, Heberer M, Oertli D, Terracciano L, Spagnoli GC, Iezzi G. Mele V, et al. Among authors: spagnoli gc. Int J Cancer. 2014 Jun 1;134(11):2583-94. doi: 10.1002/ijc.28598. Epub 2014 Jan 30. Int J Cancer. 2014. PMID: 24214914 Free PMC article.
GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.
Nebiker CA, Han J, Eppenberger-Castori S, Iezzi G, Hirt C, Amicarella F, Cremonesi E, Huber X, Padovan E, Angrisani B, Droeser RA, Rosso R, Bolli M, Oertli D, von Holzen U, Adamina M, Muraro MG, Mengus C, Zajac P, Sconocchia G, Zuber M, Tornillo L, Terracciano L, Spagnoli GC. Nebiker CA, et al. Among authors: spagnoli gc. Clin Cancer Res. 2014 Jun 15;20(12):3094-106. doi: 10.1158/1078-0432.CCR-13-2774. Epub 2014 Apr 15. Clin Cancer Res. 2014. PMID: 24737547
Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".
Hirt C, Papadimitropoulos A, Muraro MG, Mele V, Panopoulos E, Cremonesi E, Ivanek R, Schultz-Thater E, Droeser RA, Mengus C, Heberer M, Oertli D, Iezzi G, Zajac P, Eppenberger-Castori S, Tornillo L, Terracciano L, Martin I, Spagnoli GC. Hirt C, et al. Among authors: spagnoli gc. Biomaterials. 2015 Sep;62:138-46. doi: 10.1016/j.biomaterials.2015.05.037. Epub 2015 May 20. Biomaterials. 2015. PMID: 26051518
The Interplay Between Neutrophils and CD8+ T Cells Improves Survival in Human Colorectal Cancer.
Governa V, Trella E, Mele V, Tornillo L, Amicarella F, Cremonesi E, Muraro MG, Xu H, Droeser R, Däster SR, Bolli M, Rosso R, Oertli D, Eppenberger-Castori S, Terracciano LM, Iezzi G, Spagnoli GC. Governa V, et al. Among authors: spagnoli gc. Clin Cancer Res. 2017 Jul 15;23(14):3847-3858. doi: 10.1158/1078-0432.CCR-16-2047. Epub 2017 Jan 20. Clin Cancer Res. 2017. PMID: 28108544
247 results