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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver.
Bertocchi A, Carloni S, Ravenda PS, Bertalot G, Spadoni I, Lo Cascio A, Gandini S, Lizier M, Braga D, Asnicar F, Segata N, Klaver C, Brescia P, Rossi E, Anselmo A, Guglietta S, Maroli A, Spaggiari P, Tarazona N, Cervantes A, Marsoni S, Lazzari L, Jodice MG, Luise C, Erreni M, Pece S, Di Fiore PP, Viale G, Spinelli A, Pozzi C, Penna G, Rescigno M. Bertocchi A, et al. Among authors: spaggiari p. Cancer Cell. 2021 May 10;39(5):708-724.e11. doi: 10.1016/j.ccell.2021.03.004. Epub 2021 Apr 1. Cancer Cell. 2021. PMID: 33798472 Free article.
Lymphatic endothelium contributes to colorectal cancer growth via the soluble matrisome component GDF11.
Ungaro F, Colombo P, Massimino L, Ugolini GS, Correale C, Rasponi M, Garlatti V, Rubbino F, Tacconi C, Spaggiari P, Spinelli A, Carvello M, Sacchi M, Spanò S, Vetrano S, Malesci A, Peyrin-Biroulet L, Danese S, D'Alessio S. Ungaro F, et al. Among authors: spaggiari p. Int J Cancer. 2019 Oct 1;145(7):1913-1920. doi: 10.1002/ijc.32286. Epub 2019 Apr 9. Int J Cancer. 2019. PMID: 30889293 Free article.
NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer.
Mikulak J, Oriolo F, Bruni E, Roberto A, Colombo FS, Villa A, Bosticardo M, Bortolomai I, Lo Presti E, Meraviglia S, Dieli F, Vetrano S, Danese S, Della Bella S, Carvello MM, Sacchi M, Cugini G, Colombo G, Klinger M, Spaggiari P, Roncalli M, Prinz I, Ravens S, di Lorenzo B, Marcenaro E, Silva-Santos B, Spinelli A, Mavilio D. Mikulak J, et al. Among authors: spaggiari p. JCI Insight. 2019 Dec 19;4(24):e125884. doi: 10.1172/jci.insight.125884. JCI Insight. 2019. PMID: 31689241 Free PMC article.
Dysfunctional Extracellular Matrix Remodeling Supports Perianal Fistulizing Crohn's Disease by a Mechanoregulated Activation of the Epithelial-to-Mesenchymal Transition.
Rizzo G, Rubbino F, Elangovan S, Sammarco G, Lovisa S, Restelli S, Pineda Chavez SE, Massimino L, Lamparelli L, Paulis M, Maroli A, Roda G, Shalaby M, Carvello M, Foppa C, Drummond SP, Spaggiari P, Ungaro F, Spinelli A, Malesci A, Repici A, Day AJ, Armuzzi A, Danese S, Vetrano S. Rizzo G, et al. Among authors: spaggiari p. Cell Mol Gastroenterol Hepatol. 2023;15(3):741-764. doi: 10.1016/j.jcmgh.2022.12.006. Epub 2022 Dec 12. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36521659 Free PMC article.
Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells.
Cortese N, Capretti G, Barbagallo M, Rigamonti A, Takis PG, Castino GF, Vignali D, Maggi G, Gavazzi F, Ridolfi C, Nappo G, Donisi G, Erreni M, Avigni R, Rahal D, Spaggiari P, Roncalli M, Cappello P, Novelli F, Monti P, Zerbi A, Allavena P, Mantovani A, Marchesi F. Cortese N, et al. Among authors: spaggiari p. Cancer Immunol Res. 2020 Apr;8(4):493-505. doi: 10.1158/2326-6066.CIR-19-0403. Epub 2020 Feb 4. Cancer Immunol Res. 2020. PMID: 32019781
Immune infiltrating cells in duodenal cancers.
Donisi G, Capretti G, Cortese N, Rigamonti A, Gavazzi F, Nappo G, Pulvirenti A, Sollai M, Spaggiari P, Zerbi A, Marchesi F. Donisi G, et al. Among authors: spaggiari p. J Transl Med. 2020 Sep 3;18(1):340. doi: 10.1186/s12967-020-02508-4. J Transl Med. 2020. PMID: 32883314 Free PMC article.
Ki-67 and presence of liver metastases identify different progression-risk classes in pancreatic neuroendocrine neoplasms (pNEN) undergoing resection.
Milione M, Maisonneuve P, Pellegrinelli A, Spaggiari P, Centonze G, Coppa J, Delconte G, Droz Dit Busset M, Lanhazo O, Pruneri G, Mazzaferro V. Milione M, et al. Among authors: spaggiari p. Eur J Surg Oncol. 2019 May;45(5):755-760. doi: 10.1016/j.ejso.2018.10.052. Epub 2018 Oct 11. Eur J Surg Oncol. 2019. PMID: 30366875
92 results